卡维地洛治疗充血性心力衰竭的临床研究  

Effects of carvedilol in patients with congestive heart failure

作　　者：赵旭[1] 郑继平[1] 杨飞[1] 

机构地区：[1]台州市第一人民医院心内科,浙江台州318020

出　　处：《心血管康复医学杂志》2003年第1期31-33,共3页Chinese Journal of Cardiovascular Rehabilitation Medicine

摘　　要：目的:探讨卡维地洛对充血性心力衰竭(CHF)患者心功能的影响。方法:45例CHF患者被随机分成2组.对照组(B组)用利尿剂、强心甙、硝酸酯类等药进行治疗,治疗组(A组)在B组治疗基础上加用卡维地洛,起始剂量3.125mg,2次/d,每2周加量1倍,至最大剂量25mg,2次/d。结果:治疗16周后,两组的心功能分级均有明显改善.与对照组比较,治疗组LVEF增加更加显著(P<0.05)。结论:卡维地洛对CHF有较好的疗效。Objective: To evaluate the effects of carvedilol on patients with congestive heart failure (CHF). Methods: Forty-five patients with CHF were randomly divided into two groups. The control group (group B) was given diuretic, cardiac glycoside and nitric acid ester, the therapy group (group A) was added with carvedilol. Carverdilol was given small dose in the beginning. Results: Sixteen weeks after treatment, the NYHA class and Left ventricular ejection fraction of all patients were improved significantly(0. 39 to 0. 50,P<0. 01 in group A;0. 38 to 0. 41,P<0. 05 in group B). Compared with control group LVEF significantly increased in therapy group (P<0. 05). Conclusion; Carvedilol is effective for the patient with CHF.

关 键 词：卡维地洛 治疗 充血性心力衰竭 临床研究 

分 类 号：R541.610.5[医药卫生—心血管疾病]