益母草提取工艺优选  

Studies on Extracting Techniques of Herba Leonuri

作　　者：刘莉[1] 高鹏[1] 李慧金[2] 

机构地区：[1]山东中医药大学,山东济南250014 [2]山东省医学科学院药物所,山东济南250014

出　　处：《中国实验方剂学杂志》2003年第2期3-5,共3页Chinese Journal of Experimental Traditional Medical Formulae

摘　　要：以浸膏特性、水苏碱含量、总生物碱含量为指标 ,比较了不同溶剂对益母草中生物碱的提取效果 ,结果表明以水为溶剂 ,经济易行 ,且能够充分地提出有效成分。以盐酸水苏碱为指标 ,采用L9(34 )正交设计法 ,优选了水提取的最佳工艺条件 ,水煎煮两次 ,第一次加 12倍量水 ,第二次加 9倍量水 ,各煎 1 5h。The extracting effects of alkaloids from Leonurus heterrophyllus by different solvents were optimized by extract properties,contents of stachydrine hydrochloride and total alkaloids.The results showed water was better extracting solvent.The optimized extracting condition were:boiling with water for two times sustaining for 1 5h each,using 12 times volume of water for first time and 9 times for the second by orthogonal designed method,by use of content of as makers.

关 键 词：益母草 提取工艺 优选 盐酸水苏碱 中药 

分 类 号：R284.2[医药卫生—中药学]