The experimental studies of Heliox decreasing airway resistance and improving pulmonary effective ventilation  

作　　者：解立新 刘又宁 马迎民 

机构地区：[1]Respiratory Laboratory,General Ho spital of PLA

出　　处：《中国临床康复》2003年第3期512-513,共2页Chinese Journal of Clinical Rehabilitation

基　　金：byProjectofPLAYouthFoundation,(PLAgeneralserviceofMinisteryofHealth98Q95)

摘　　要：AIM:The study evaluated the effects of br eathing helium-oxygen(79%heliox and 21%oxygen)on respiratory insufficiency by way of experimental and clinical observations.METHODS:Six mongrel dogs were randomly inspi red air or heiox after dripping 2%methac holine in tracheas controlled by 900C ventilator.During the experimenta l course,respiratory mechanical li mits,hemodynamic index and blood gas valu es were observed.Six ventilated pa-tients with COPD in the respiratory i ntensive care unit inspired heliox,and the data of respiratory mechanics were r ecorded.RESULTS:The results demon-strate that heliox can reduce airway resistance,airway pressure,and wo rk of breathing,improve lung effective c ompliance,but heliox has no side eff ects on pulmonary circulation and systemic circulation.Heliox improves oxyge n dif-fusion and CO 2 climinating.CONCLUSION:Breathing heliox is one of the effective ways for patients with sev ere obstructive pulmonaryAIM:The study evaluated the effects of br eathing helium-oxygen(79%heliox and 21%oxygen)on respiratory insufficiency by way of experimental and clinical observations.METHODS:Six mongrel dogs were randomly inspi red air or heiox after dripping 2%methac holine in tracheas controlled by 900C ventilator.During the experimenta l course,respiratory mechanical li mits,hemodynamic index and blood gas valu es were observed.Six ventilated pa-tients with COPD in the respiratory i ntensive care unit inspired heliox,and the data of respiratory mechanics were r ecorded.RESULTS:The results demon-strate that heliox can reduce airway resistance,airway pressure,and wo rk of breathing,improve lung effective c ompliance,but heliox has no side eff ects on pulmonary circulation and systemic circulation.Heliox improves oxyge n dif-fusion and CO 2 climinating.CONCLUSION:Breathing heliox is one of the effective ways for patients with sev ere obstructive pulmonary diseases

关 键 词：氦-氖混合气 降低 气道阻力 肺 有效通气 实验研究 

分 类 号：R459.6[医药卫生—治疗学]