NaHSO_4·H_2O催化合成苯甲酸甲酯(英文)  

Synthesis of Methyl Benzoate Catalyzed by NaHSO_4·H_2O

作　　者：文瑞明[1] 雷存喜[1] 丁亮中[1] 俞善信[1] 

机构地区：[1]湖南城市学院化学系,湖南益阳413049

出　　处：《合成化学》2003年第1期89-92,共4页Chinese Journal of Synthetic Chemistry

基　　金：Supported by the Natural Science Foundation of Hunan Province(0 0 JJY2 0 1 1 0 ) and Scientific Re-search Fund of Hunan Provincial Education Department(0 1 C0 2 2

摘　　要：以 Na HSO4 · H2 O催化苯甲酸与甲醇的酯化反应 ,合成了苯甲酸甲酯。研究结果表明 ,Na HSO4 · H2 O具有较高的催化活性。考察了苯甲酸 /甲醇摩尔比、催化剂用量及反应时间对酯产率的影响。在优化反应条件 [n(苯甲酸 )∶n(甲醇 )∶n( Na HSO4 ·H2 O) =1∶ 2∶ 0 .2 9,回流8h]下 ,苯甲酸甲酯产率达 85.3 %。Methyl benzoate was synthesized by esterification of benzoic acid with methyl alcohol using NaHSO 4·H 2O as a catalyst. The experimental results indicated that the catalyst possessed high catalytic activity for the esterification reaction. The synthetic conditions have been optimized, including the molar ratio of benzoic acid to methyl alcohol, the amount of catalyst used and the reacting time. The yield of the ester obtained under the optimal reaction conditionsn(benzoic acid)∶n(methyl alcohol)∶n(NaHSO 4·H 2O)=1∶2∶0.29, refluxing for 8h] was 85.3%. was 85.3%.

关 键 词：催化合成 酯化 苯甲酸 甲醇 苯甲酸甲酯 NaHSO4·H2O 硫酸氢钠 

分 类 号：O625.523[理学—有机化学] O643.36[理学—化学]