稀土矿区婴幼儿与其母亲头发中稀土含量的研究  

Relationship of the hair content of rare earth elements in young children aged 0 to 3 years to that in their mothers living in a rare earth mining area of Jiangxi

作　　者：彭瑞玲[1] 潘小川[1] 解清[2] 

机构地区：[1]北京大学公共卫生学院劳动卫生与环境卫生学系,100083 [2]北京大学公共卫生学院中心实验室,100083

出　　处：《中华预防医学杂志》2003年第1期20-22,共3页Chinese Journal of Preventive Medicine

基　　金：国家自然科学基金资助 ( 2 9890 2 80 )

摘　　要：目的　探讨稀土矿区婴幼儿与其母亲头发中的稀土含量 ,以及二者的关系。方法　采用电感耦合等离子质谱法对 71名婴幼儿及 62名母亲的发根部头发进行镧、铈、镨、钕、钐 5种稀土元素的测定。结果　独立样本均数比较发现 ,婴幼儿和母亲头发 5种稀土元素均为高暴露区 >低暴露区 >对照区。如镧元素 ,婴幼儿发中水平为高暴露区 (2 2 0 2 90ng/g) >低暴露区 (471 72ng/g) >对照区 (97 37ng/g) ,母亲发中水平为高暴露区 (1 51 0 2 1ng/g) >低暴露区 (2 4 1 63ng/g) >对照区 (59 1 5ng/g) ;配对均数比较发现 ,5种稀土元素水平均为婴幼儿高于其母亲约 2倍。如镧元素 ,婴幼儿发中水平为 533 83ng/g,而母亲为 2 79 78ng/g ;简单相关分析发现 ,婴幼儿与其母亲发中 5种稀土元素均有显著相关性 ,相关系数均在 0 75以上。结论　头发作为稀土暴露研究的生物标志物具有一定的可行性 ;随着暴露程度的增加 ,头发中稀土有蓄积的趋势 ;稀土矿区婴幼儿发中各稀土元素含量明显高于其母亲 。Objective To study the relationship of hair content of rare earth elements (REEs) in the young children aged 0?-3 years to that in their mothers living in a rare earth mining area of Jiangxi Province Methods Content of five kinds of REEs, i e , lanthanum (La), cerium (Ce), praseodymium (Pr), neodymium (Nd) and samarium (Sm) were determined for the hair root samples collected from 71 young children and 62 of their mothers by inductively coupled plasma source mass spectrometry (ICP MS) Results The mean hair content of REEs (e g , La) was the highest (2 202 90 ng/g) in the young children living in the place nearest to the REE mining area, next (471 72 ng/g) was in those nearer to the REE mining area, and the lowest (97 37 ng/g) was in those in the control area And, the hair content of REEs in the mothers was the same as that in their children, i e, the mean content of La was the highest (1 510 21 ng/g) in high exposure area, next (241 63 ng/g) was that in the low exposure area, and the lowest (59 15 ng/g) was that in the control area, with P <0 001 Pair comparison analysis for the means showed that the average hair level of five kinds of REEs in the young children was two times high as their mothers' ( P <0 001) For example, the hair level of La was 533 83 ng/g in the young children and 279 78 ng/g in their mothers, respectively Simple linear regression analysis showed that there was a significant correlation between the hair levels of each kind of REEs in the young children and those in their mothers, with a correlation coefficient of more than 0 75, e g , that of La was 0 878 ( P <0 01) Conclusions The hair level of REEs can be used as a bio marker to reflect body's level of exposure to REEs The hair level of REEs in young children and their mothers decreased with the increase of the distance from their home to rare earth mining area Young children living in the area with REEs mining may be the high exposure population, and their hair level of REEs was signif

关 键 词：稀土矿区 含量 稀土 毛发 婴幼儿 母亲 

分 类 号：R174[医药卫生—妇幼卫生保健]