中药复方肠安泰预防大肠癌术后转移80例临床观察  

Clinical Observation of the Preventive Effects of Chang'antai on Postoperative Metastasis of Carcinoma of Large Intestine in 80 Cases

作　　者：王文萍[1] 王垂杰[1] 刘放[2] 姜良铎[3] 胡志敏[1] 孙维刚[1] 贾智捷[1] 刘姣[1] 史丽萍[1] 邢玉庆[1] 邱岩[2] 

机构地区：[1]辽宁中医学院附属医院,辽宁110032 [2]辽宁省肿瘤医院,辽宁110042 [3]北京中医药大学东直门医院,北京100029

出　　处：《北京中医药大学学报》2003年第2期60-62,共3页Journal of Beijing University of Traditional Chinese Medicine

基　　金：辽宁省科学基金委员会基金资助课题 (No .962 2 43 )

摘　　要：目的　探讨肠安泰对大肠癌术后和转移的预防及血清CEA、外周血WBC的影响。方法　 80例大肠癌术后转移患者随机分为中药组、化疗组、中药加化疗组。结果　各组转移率无显著性差异 ,术后血清CEA含量下降以中药组较早 ,有显著意义 (P <0 0 5 )。化疗后各组WBC均有明显下降 ,以化疗组下降最为明显 ,且有显著性差异 (P <0 0 5 )。化疗组治疗后的生存质量明显降低 ,有显著性差异 (P <0 0 5 )。结论　肠安泰能够明显提高患者的生存质量 ,减轻化疗的毒副反应 ,增强肝脏清除血清CEA的能力 ,降低血清CEA。Objective To investigate the preventive effects of Chang'antai on postoperative metastasis of carcinoma of large intestine and the effects of the same medicine on the level of CEA in the serum and WBC count of the peripheral blood. Method 80 Cases of postoperative metastasis of carcinoma of large intestine were randomly divided into the Chang'antai group, chemotherapy group and Chang'antai plus chemotherapy group. Results There was no significant difference between the rates of postoperative metastasis in all the three groups; the postoperative level of CEA in the serum decreased earlier in the Chang'antai group than in other groups ( P <0 05); WBC count markedly decreased in the groups receiving chemotherapy, particularly in the chemotherapy group ( P <0 05); and also, the quality of life remarkably lowered in the chemotherapy group ( P <0 05). Conclusion Chang'antai can markedly increase the patients'quality of life, decrease the toxic and side effects of chemotherapy, and enhance the ability of the liver to clear out CEA in the serum.

关 键 词：肠安泰 大肠癌 术后转移 预防 

分 类 号：R273.534[医药卫生—中西医结合]