卡维地洛对充血性心衰患者心脏功能的影响  

Carvedilol in treatment of chronic heart failure

作　　者：石小鹏[1] 唐荔[1] 席晓萍[2] 王汝娟[1] 

机构地区：[1]第四军医大学西京医院药剂科,西安710032 [2]武警北京总队医院特检科

出　　处：《第二军医大学学报》2003年第3期341-342,共2页Academic Journal of Second Military Medical University

摘　　要：将符合本试验纳入标准的 88例充血性心衰患者分成试验组 (40例 )和对照组 (48例 ) ,患者均口服地高辛、血管紧张素转换酶抑制剂制剂、血管扩张剂 (非钙离子拮抗剂 )和利尿剂等基本抗心衰药物 ,在此基础上试验组加服卡维地洛。随访 7个月后 ,复查心脏彩超心脏射血分数和左室短轴缩短率 ,与试验初比较两组均有显著的改善 ,而服药 7个月后试验组较对照组有显著的升高 (P <0 .0 5 )。表明卡维地洛可使心肌重塑过程得到缓解 。A total of 88 patients with chronic heart failure were divided into 2 groups: the carvedilol group( n =40) and the control group( n =48). Patients in 2 groups were all treated with routine regime,the experimental group also received carvedilol treatment.Before and 7 months after treatment, their left ventricular ejection fractions (EF%) and the rate of left ventricular drawing back on short axis contration were recorded to evaluate the effects of carvedilol. The values of EF% and short axis were higher in both groups after 7 months follow up ( P <0.05), but they were significantly higher in patients treated with carvedilol than those with control drugs. Carvedilol added to other basic drugs is benefitial for the prognosis of the patients with the heart failure.

关 键 词：卡维地洛 充血性心力衰竭 心脏射血分数 

分 类 号：R972.1[医药卫生—药品] R541.61[医药卫生—药学]