葛根素对冠心病患者心肌缺血的疗效  

Therapeutic efficacy of puerarin in coronary heart disease patients with myocardial ischemia

作　　者：祝星[1] 鱼运寿[2] 李仁君[2] 董小玲[2] 

机构地区：[1]宁波市第一医院心内科,宁波315010 [2]宁波市第一医院动态心电图室

出　　处：《第二军医大学学报》2003年第3期343-344,共2页Academic Journal of Second Military Medical University

摘　　要：为观察葛根素对冠心病患者心肌缺血的治疗作用 ,将 6 0例冠心病心肌缺血患者随机分为葛根素组 (30例 ,常规西药加葛根素注射液治疗 )与对照组 (30例 ,单用常规西药治疗 )。结果显示 ,治疗后葛根素组的心肌缺血总负荷下降幅度明显大于对照组 (P <0 .0 1) ,心率、收缩压有所下降但不明显 (P >0 .0 5 ) ,室性期前收缩有明显减少 (P <0 .0 5 )。在治疗期间无明显不良反应。本研究认为葛根素是一种安全。Toassesstheeffectofpuerarinintreatingischemiacardiacdisease ,sixtycoronaryheartdisease(CHD) patientswith myocardialischemiawererandomlydividedinto 2 groups.Pueraringroup (30cases)wastreatedwithpuerarinpluswesternmedicine andcontrolgroup (30cases)withwesternmedicinealone .Thechangesofthetotalischemiaburden (TIB) ,ventricularpremature beat (VPB) ,heartrateandsystolicpressurelevelswereobservedbeforeandaftertreatmeat.Aftertreatmentwithpuerarinthe scoresofTIBlevelsweresignificantlydecreased (P <0 .0 1) ,Thescoresofheartrateandsystolicpressureweredecreasedwithno significance (P >0 .0 5 ) .Thescoresofventricularprematurebeatlevelsweresignificantlydecreased (P <0 .0 5 ) .Intheperiodof treatment,nosideeffectswerefound .Thestudyshowedthatpuerarinwasasafe ,efficientdrugintreatingmyocardialischemiaof coronaryheartdisease . [

关 键 词：葛根素 冠状动脉疾病 心肌缺血 缺血总负荷 

分 类 号：R286.2[医药卫生—中药学]