蒺藜皂苷对乳腺癌细胞Bcap-37的体外抑制作用  

The Inhibitory Effect of Saponins from Tribulus terrestris on Bcap-37 Breast Cancer Cell Line in Vitro

作　　者：孙斌[1] 瞿伟菁[1] 柏忠江[1] 

机构地区：[1]华东师范大学生命科学学院,上海200062

出　　处：《中药材》2003年第2期104-106,共3页Journal of Chinese Medicinal Materials

摘　　要：采用生长曲线法、MTT法、蛋白质含量测定以及形态学方法观察了蒺藜皂苷(STT)对于体外培养Bcap-37细胞抑制作用,结果显示:STT对于Bcap-37细胞增殖有较强的抑制作用,且呈明显的剂量与时间依赖关系,经STT作用后,细胞形态学表现为细胞变圆、皱缩,核固缩、浓聚。The inhibitory effect of saponins from Tribulus terrestris (STT) on Bcap37 breast cancer cell line were determined by cell growth curve, MTT assay, protein content assay and morphological observation.The results showed that STT had potent inhibitory effect on Bcap-37 cell line in a concentration-dependent manner. Bcap-37 cell exhibited morphological alteration, namely, cells got round and shrunk, nuclei contracted after treating with STT.

关 键 词：蒺藜皂苷 乳腺癌 Bcap-37细胞株 中药 细胞毒作用 

分 类 号：R273.79[医药卫生—中西医结合]