偶氮氯膦Ⅲ光度法测定1,6-二磷酸果糖锶盐中的锶含量  

Spectrophotometric determination of strotium with a reagent azochlorthoate and its apllication

作　　者：程艳菊[1] 王龙根[1] 应汉杰[1] 赵谷林[1] 欧阳平凯[1] 

机构地区：[1]南京工业大学制药与生命科学学院,江苏南京210009

出　　处：《南京工业大学学报（自然科学版）》2003年第2期71-74,共4页Journal of Nanjing Tech University(Natural Science Edition)

基　　金：江苏省新世纪学科带头人培养人选基金资助

摘　　要：研究了偶氮氯膦Ⅲ分光光度法测定1,6 二磷酸果糖锶盐中锶的质量浓度的方法。实验表明,在pH3 4的邻苯二甲酸 邻苯二甲酸氢钾缓冲介质中,当Tween 80存在时,锶与偶氮氯膦Ⅲ形成蓝紫色络合物,它的最大吸收峰位于660nm。锶的质量浓度在0～1 0μg/mL范围内符合比耳定律且具有高选择性,表观摩尔吸光系数为4 33×104L·mol-1·cm-1,相关系数R2=0 9998,回收率为97 41%～101 9%。A spectrophotometric method for determination of strontium with a reagent azochlorthoate was studied. In the medium of a KHC8H4O4HCl buffer solution of pH 3.2, strontium formed a bluepurple complex with azochlorthoate in the presence of Tween80. The strontium complex had absorbance maxium at 660 nm and its apparent molar absorptivity was 4.25×104 L·mol-1·cm-1. In the range of 0～10 μg/mL for strontium, the Beer's law was obeyed, with correlation coefficient of 0999 8. The method had a high selectivity and was applied to determine the strontium in drugs with satisfactory results, in which the recoveries were in the range of 97.7%～102.3%.

关 键 词：分光光度法 锶 偶氮氯膦Ⅲ 

分 类 号：TQ460.72[医药卫生—药物分析学]