丹参对大鼠肺水肿时E-选择素变化的影响  

Effect of Multiorrhizae on Change of E-selectin in Rat Lung of Edema

作　　者：吴山[1] 盛延良[2] 蒋志学[2] 孙明[2] 

机构地区：[1]重庆医科大学临床学院,重庆410016 [2]佳木斯大学,黑龙江佳木斯154002

出　　处：《辽宁中医杂志》2003年第3期172-173,共2页Liaoning Journal of Traditional Chinese Medicine

摘　　要：目的 :研究丹参对大鼠肺水肿时E 选择素变化的影响。方法 :利用氯气造成大鼠反应性肺水肿 ,利用ELISA方法测定大鼠血中E 选择素浓度。结果 :肺水肿时E 选择素水平明显上升 ,应用丹参后E 选择素水平可下降约 5 0 %。结论 :丹参可降低E 选择素水平 。Objective :We studied the effect of miltiorrhizae on the change of the concentration of E selectin in plasm of rat lung model of edema. Methods :the rat lung model of edema was prepared by being exposed to chlorine gas.double antibody sandwich quantitative ELISA method was used to measure the concentration of E selectin. Results :the plasma concentration of E selectin in rat exposured to chlorine gas were increased significantly in lung edema group,but that were decreased by 50% in miltiorrhizae group. Conclusions :miltiorrhizae can reduce the plasm concentration of E selectin,miltiorrhizae possessed protective effects on lung edema.

关 键 词：丹参 大鼠 肺水肿 E-选择素 

分 类 号：R259.416.3[医药卫生—中西医结合]