系统性红斑狼疮患者医院感染的调查研究  

A prospective study of nosocomial infection in patients with systemic lupus erythematosus

作　　者：徐刚[1] 刘美琳[1] 余开梅[1] 

机构地区：[1]武汉大学人民医院皮肤科,430060

出　　处：《中华风湿病学杂志》2003年第4期214-219,共6页Chinese Journal of Rheumatology

摘　　要：目的　了解系统性红斑狼疮 (SLE)患者的医院感染情况。方法　对 1995年 3月至2 0 0 2年 3月新入院的 4 5 6例SLE患者的医院感染进行调查。结果　SLE患者医院感染率为 36 4 % ,呼吸道 4 5 2 % ,泌尿道 16 0 % ,皮肤 12 6 % ,其他 2 6 2 %。以G-杆菌感染为主 ,致病菌对抗生素耐药率较高。结论　医院感染的易发因素是大量使用抗生素、激素及免疫抑制剂等。Objective To study the nosocomial infection in the patients with systemic lupus erythematosus (SLE). Methods A prospective survey of nosocomial infection in 456 cases with SLE was carried out for 84 months.Result Incidence of nosocomial infection in patients with SLE was 36 4%,infection of respiratory tract accounted for 45 2%,infection rates in urinary tract,skin and other regions were 16 0%,12 6% and 26 2% respectively.Gram negative bacilli were the predominant pathogens and the pathogens had higher frequency of multiple antibiotic resistance. Conclusion The factors related to nosocomial infection were the use of broadspectrum antibiotics,prednisone and administration of immunosuppressant,etc.

关 键 词：系统性红斑狼疮 医院感染 调查研究 

分 类 号：R593.241[医药卫生—内科学] R181.34[医药卫生—临床医学]