C-反应蛋白与不稳定性心绞痛关系的相关分析  

Analysis of the Correlation between Serum C-reactive Protein and Unstable Angina Pectoris

作　　者：刘柏年[1] 孙根义[1] 

机构地区：[1]天津市胸科医院心内二科,300051

出　　处：《天津医药》2003年第4期204-206,共3页Tianjin Medical Journal

摘　　要：目的 :研究血清C_反应蛋白 (CRP)水平与不稳定性心绞痛 (UAP)发病的关系。方法 :应用免疫浊度法测定不稳定性心绞痛组 (72例 )和对照组 (95例 )血清CRP浓度 ,同时测定同期UAP组的血脂、血糖等项指标 ,并行冠状动脉 (冠脉 )造影检查。结果 :(1)UAP组CRP水平明显高于对照组(P<0.01)。(2)UAP组CRP水平不受高胆固醇血症、高血压、吸烟、糖尿病和冠心病家族史等已知冠心病危险因子及性别的影响。(3)UAP组CRP水平与病变冠脉狭窄程度记分无直线相关性(P>0.05)。结论 :CRP是冠心病的一项独立危险因子 。Objective:To study the correlation between serum C_reactive protein(CRP)and the pathogenesis of unstable angina pectoris(UAP).Methods:The serum concentrations of C_reactive protein were measured in72patients with UAP and95healthy controls by immunonephelometry.Meanwhile the blood lipids and blood sugar were measured,and the coronary angiography were conducted in the patients with UAP.Results:(1)The levels of serum CRP in UAP patients were significantly higher than those in controls(P<0.01).(2)The levels of serum CRP were not affected by the risk factors of coronary heart disease such as hypercholestorolemia,hyperˉtension,smoking,diabetes mellitus,and the family history of coronary heart diseases as well as sex.(3)The levels of CRP in UAP patients were not related to the lesion scores of coronary arteries that reflect degree of stenosis(P>0.05).Conclusion:CRP is another independent risk factor of coronary heart disease.The pathogenesis of UAP is related to inflammation of atherosclerosis plaque in coronary artery.

关 键 词：C-反应蛋白 不稳定性心绞痛 相关分析 

分 类 号：R541.4[医药卫生—心血管疾病]