冠心病肾阳虚证血脂特点  

The Lipidic Characteristics of Kidney-Yang Deficiency Syndrome in Coronary Heart Disease

作　　者：郭平清[1] 林求诚[2] 郭银庚[2] 沈宗国[2] 

机构地区：[1]福建医科大学附属第一医院,福州350005 [2]福建中医学院

出　　处：《浙江中西医结合杂志》2003年第4期208-210,共3页Zhejiang Journal of Integrated Traditional Chinese and Western Medicine

基　　金：福建省教委科研基金项目 (K90 0 49)

摘　　要：目的 :了解肾阳虚证在冠心病不同亚型中的地位及其血脂特点。方法 :对 1 8例心肌梗死和43例心绞痛住院患者检测 2 4小时尿 1 7羟及 TC、TG、HDLc、HDL3c、HDL- PL。冠心病诊断参照WHO标准 ,肾阳虚证参照 2 4小时尿 1 7羟低于正常值。结果 :1冠心病肾阳虚证发生率与西医分型关系密切 ,心肌梗死肾阳虚证发生率 ( 1 3/1 8)显著高于心绞痛组 ( 1 3/43) ;2冠心病肾阳虚证HDL3c、 HDL - PL显著低于其它证型。结论 :冠心病肾阳虚证血脂代谢严重紊乱 ,以胆固醇逆向转运障碍进一步加重为特征。Objective: To explore the role of kidney yang deficiency syndrome (KYDS,肾阳虚证) in coronary heart disease(CHD) and its lipid characteristic.Methods:24 hours urinary 17 hydroxycosticosteroid(17 OHCS) serum lipids, including total cholesteroi(TC),triglycerides(TG),high density iipoprotein 3 cholesterol(HDL3c), high density lipoprotein phospholipids(HDL PL) were measured in 61 patients, with 18 cases of myocardial infarction(MI) and 43 cases of angina pectoris. CHD was diagnosed by WHO standard, and KYDS was based on that whose 24 urinary 17 OHCS was lower than normal level.Results: The Ocurrence of KYDS in CHD was closely related with its different forms.The occurrence ratio of KYDS in MI(13/18) was significantly higher than that in AP(13/43); serum levels of HDL 3c and HDL PL in CHD with KYDS were significantly lower than that in other syndromes. Conclusion:The metabolism of lipid was in disorder in CHD with KYDS, and its dysfuction of reverse cholesterol transport got more serious.

关 键 词：冠心病 肾阳虚证 血脂特点 高密度脂蛋白 高密度脂蛋白磷脂 胆固醇逆向转运 血脂代谢紊乱 

分 类 号：R259[医药卫生—中西医结合]