医院感染病原菌及耐药性分析  

Analysis of pathogens causing hospital infection and antimicrobial resistance

作　　者：杨宝忠[1] 沈江涌[1] 朱琪[1] 

机构地区：[1]宁夏医学院附属医院,宁夏银川750004

出　　处：《中国感染控制杂志》2003年第1期44-45,61,共3页Chinese Journal of Infection Control

摘　　要：目的　了解医院感染病原菌的分布及耐药情况。方法　对临床分离的医院感染病原菌及耐药性和社区感染病原菌进行分析。结果　该年度共出院 15 5 4 2人次 ,10 2 7人发生医院感染 10 77次 ,医院感染发病率为6 .6 % ,例次发病率为 6 .9%。 10 2 7名病人中 ,共分离出病原菌 132株 ,3/ 4的病原菌为革兰阴性菌 ,其中铜绿假单胞菌所占比例最高 ,达总数的 2 2 .7%。铜绿假单胞菌对羧苄青霉素耐药率达 6 6 .7% ,对庆大霉素的耐药率更高达77.3% ,而对头孢哌酮的耐药率也达到 5 0 .0 %。结论　医院感染病原菌主要为革兰阴性条件致病菌 ,对常用的抗菌药物耐药率较高 。Objective To study the pathogens causing hospital infection and antimicrobial resistance in a tertiary teaching hospital. Methods The data of resistant bacteria isolated from patients with nosocomial and community acquired infections were analysed. Results One thousand and twenty seven patients developed 1 077 cases of nosocomial infection (NI), the incidence was 6.93% . 132 pathogenic strains were isolated from 1 027 patients, about 3/4 of which were Gram negative bacteria, most were Pseudomonas aeruginosa, which accounting for 22.7% of all 132 isolates. The resistant ratio of Pseudomonas aeruginosa to carbenicillin, gentamycin and cefoperazone were 66.7% , 77.3% and 50.0% respectively. Conclusion Most pathogens isolated from patients with hospital infection were Gram negative bacteria, which always has multi resistant tendency to commonly used antimicrobial aegents.

关 键 词：医院感染 病原菌 耐药性分析 治疗 

分 类 号：R181.34[医药卫生—流行病学]