三种纤维蛋白原测定方法的比较  

A comparison of three methods in determination of plasma fibrinogen

作　　者：秦红[1] 陈金来[1] 李晔[1] 李忠信[1] 

机构地区：[1]天津医科大学第二医院检验科,300211

出　　处：《江西医学检验》2002年第6期325-326,342,共3页Jiangxi Journal of Medical Laboratory Sciences

摘　　要：目的探讨溶栓药物降纤酶治疗的病人血浆纤维蛋白原(Fib)的结果在不同测定方法间的差异。方法亚硫酸钠盐分析法、免疫比浊法与克劳斯法分别对40例健康人和20例降纤酶治疗后病人的血浆进行测定。结果三种方法对40例正常血浆测定结果无显著性差异,而对降纤酶治疗后病人的血浆测定结果有显著性差异。结论亚硫酸钠盐析法、免疫比浊法对纤维蛋白测定结果偏高,克劳斯法比较准确。Objective To investigate the difference of plasma fib rinogen levels in patients treated with defibrase by different determining methods.Method The plasma fibrinogen from40healthy persons and20patients treated were measured by sodium sulphite(salt precipitation)assay,immunoturbility assay and von clauss method respec-tively.Result The results of the40healthy persons showed no significant difference amoung sodium sulphite,immunoturbidity assay and von clauss method,but that of20patients showed significant difference.Conclusion The level of plasma Fib measured by sodium sulphite assay and immunobidity assay are higher than that of von clauss method,and von elauss method is more dependable.

关 键 词：纤维蛋白原 血浆 克劳斯法 亚硫酸钠盐析法 免疫比浊法 降纤酶 

分 类 号：R446.119[医药卫生—诊断学]