高频部分液体通气对吸入性损伤犬呼吸功的影响  

High frequency partial liquid ventilation on the work of breathing in dogs with inhalation injuries

作　　者：钱克俭[1] 郭光华[2] 赵为禄[1] 

机构地区：[1]江西医学院第一附属医院ICU,南昌330006 [2]江西医学院第一附属医院烧伤科,南昌330006

出　　处：《中华急诊医学杂志》2003年第2期92-93,共2页Chinese Journal of Emergency Medicine

基　　金：国家自然科学基金资助项目 ( 3 9760 0 73 );江西省主要学科跨世纪学术和技术带头人培养计划 (K990 5 0 2 )

摘　　要：目的　观察高频喷射通气结合小剂量氟碳 (3ml/kg)液体通气对吸入性损伤犬呼吸的功影响。方法　将 16条犬经蒸气吸入造成吸入性损伤模型 ,并随机分为两组 ,即对照组和治疗组。两组动物致伤后均行高频喷射通气 ,但治疗组动物同时经气管导管将氟碳液体 (3ml/kg)缓慢注入肺内 ,在 90min内测机械通气功 (WOBvent)。结果　治疗组在给予小剂量氟碳后的WOBvent与致伤后比较差异无显著意义 (P >0 0 5 ) ,对照组治疗后的WOBvent与致伤后比较差异亦无显著意义 (P >0 0 5 ) ,治疗组与对照组各时间点的WOBvent比较差异均无显著意义 (P >0 0 5 )。结论　高频喷射通气合并小剂量氟碳 (3ml/kg)部分液体通气并不增加动物的呼吸功。Objective To study high frequency jet ventilation combined with perfluorocarbon partial liquid ventilation on the work of breathing after inhalation injuries.Methods 16 dogs with inhalation injuries from steam were divided into control group and treatment group at random.Both groups were given high frequency jet ventilation after injury,and treatment group simultaneously received perfluorocarbon liquid (3ml/kg) injected into lungs slowly.The work of breathing was examined at different time over 90 minutes.Results There is no statistical difference in the work of breathing between two group.Conclusion High frequency jet ventilation combined with low volume perfluorocarbon(3ml/kg) liquid ventilation do not increase the work of breathing. [

关 键 词：吸入性损伤 高频喷射通气法 氟碳液体通气法 呼吸功 犬 

分 类 号：R563.8[医药卫生—呼吸系统]