胆甾醇乙酸酯液晶的合成  

Synthesis of Cholesteryl Acetate Liquid Crystalline

作　　者：王培义[1] 闫铨钊[1] 赵金凤[1] 

机构地区：[1]郑州轻工业学院化工系,河南郑州450002

出　　处：《河南化工》2003年第2期17-18,共2页Henan Chemical Industry

摘　　要：采用胆甾醇与乙酸酐直接酯化法合成胆甾醇乙酸酯,优化后的工艺条件为:n(乙酸酐):n(胆甾醇)=1.9～2.0:1,反应温度80％,反应时间3 h,在此条件下,产率可达95％以上;经无水乙醇重结晶,纯度达99％以上。产品的熔点为97.5℃,清亮点为113℃,IR谱图分析和元素分析结果表明,产物纯度较高。The cholesteryl acetate is synthesized by direct esterification of cholesterol and acetic anhydride. The optimal synthetic conditions obtained are as follows : The molar ratio of acetic anhydride to cholesterol is 1.9 -2.0:1, reaction time 3h and reaction temperature 80ccccccccccccc. The yield of cholesteryl acetate is above 95% . The product is recrystallized by absolute ethyl alcohol and the purity of the product obtained is above 99% . The melting point is 97.5cccccccccccccc and liquid crystalline phase temperature is 113ccccccccccccccc . IR Analysis and element analysis show that the purity of product is higher.

关 键 词：胆甾醇乙酸酯 液晶 合成 乙酸酐 直接酯化法 

分 类 号：O753.2[理学—晶体学] O623.624