内科疾病患者乙型肝炎病毒感染血清学调查  

HBV Infection in Medical Patients: A Serology Study

作　　者：吴正林[1] 朱国都[1] 

机构地区：[1]广东医学院附属深圳福田医院,广东深圳518033

出　　处：《中华医院感染学杂志》2003年第2期113-115,共3页Chinese Journal of Nosocomiology

摘　　要：目的　了解内科疾病患者人群乙型肝炎病毒 (HBV)感染和流行情况 ,为疾病诊断、防治工作提供参考依据。方法　用ELISA法作HBV血清学五项指标 (两对半 )检测 ,将 186 0位内科疾病患者按科室主要分为消化、肾病、呼吸、心血管、内分泌、神经 6大疾病组 ,对其电脑存档的临床检验资料进行统计分析。结果　共检出 19种两对半模式 ,特殊模式较多出现 ;共检出HBsAg阳性 345例 ,总阳性率为 18.5 5 % ,明显高于对照组水平 10 2 0 % ,具有显著性意义 (χ2 =19.5 9,P <0 .0 0 5 ) ;男性患者HBsAg阳性率为 2 0 .80 % ,女性患者阳性率为 16 0 6 % ,男性明显高于女性 ,有显著性意义 (χ2 =5 .5 8,P <0 .0 2 5 ) ;各疾病组HBsAg阳性率依次为 2 1.0 1%、19.0 2 %、19.85 %、16 .85 %、16 5 0 %、15 .32 % ,其中消化、肾病、呼吸疾病组HBsAg阳性率略高于总体平均水平 ,但无显著性意义 (χ2 =4 .19,V =5 ,0 .75 >P >0 .5 )。结论　内科疾病患者人群HBV感染严重 ,常规检查肝功能、两对半不可忽视。OBJECTIVE To comprehend the HBV infection and epidemic circumstances of the sufferers from internal diseases, furnish the reference evidences for the diagnoses and prevention and cure.METHODS In ELISA to test the five HBV serology targets (two couples and a half). According to the subjects to divide the 1 860 cases of sufferers from internal diseases mainly into six disease groups as digestive diseases, kidney diseases, respiratory diseases, cardiovascular diseases, endocrin ological diseases and neurological diseases and the statistics show the clinical examining data filed in computer.RESULTS ①Test out 19 types of ' two couples and a half' models totally, the special models appear fairly more. ②Test out 345 cases with positive HBsAg totally. The total positive rate is 18.55% (345/1 860), clearly higher than the level of the control which is 10.20% (51/500), and the difference is significant (χ 2=19.59, P<0.005). ③ The HBsAg positive rate of the male patients is 20.80%(203/976), higher than the female 16.06% (142/884), and the difference is significant (χ 2=5.58, P<0.025). ④In turn the HBsAg positive rates of various disease groups are 21.01%, 19.02%, 19.85%, 16.85%, 16 50%, 15.32%, respectively among them the HBsAg positive rates in digestive, kidney, respiratory diseases groups are a little higher than the whole average level, but the difference is not significant(χ 2=4.19, V=5, 0.75>P>0.5). CONCLUSIONS The HBV infection is serious of the sufferers from medical diseases, it′s not to be ignored to routine test the liver function and 'two couples and a half'.

关 键 词：内科疾病 患者 乙型肝炎病毒感染 血清学调查 诊断 防治 

分 类 号：R512.62[医药卫生—内科学]