创伤患者伤口感染常见病原菌及抗生素的选择  

Common Bacteria Distribution and Antibiotics Choice in Trauma Patients with Wounds

作　　者：王君韬[1] 李英[1] 谈建[1] 

机构地区：[1]天津医院,天津300211

出　　处：《中华医院感染学杂志》2003年第2期168-170,共3页Chinese Journal of Nosocomiology

摘　　要：目的　研究创伤患者伤口感染的常见病原菌及对常用抗生素的耐药性 ,以指导临床抗生素的选择。方法　对 1996～ 2 0 0 0年间在我院就诊的创伤患者不愈合伤口分泌物标本进行细菌学培养及药物敏感测定。结果　 35 4 5例次伤口分泌物标本中分离出致病菌 2 396株 ,细菌检出阳性率为 6 7.5 9% ,列前 5位的细菌分别是金黄色葡萄球菌、表皮葡萄球菌、铜绿假单胞菌、肠球菌和大肠埃希菌 ,金黄色葡萄球菌对常用抗生素的耐药率超过 80 % ,亚胺培南 /西司他丁及万古霉素仍是治疗革兰阳性球菌的有效药物 ,革兰阴性杆菌对第三代头孢菌素的耐药率较高。结论　开展创伤患者伤口感染细菌培养及耐药性监测有重要意义 ,有利于合理使用抗生素。OBJECTIVE The distribution and antibiotics resistance of common bacteria in the trauma patients with wounds were studied to direct the using antibiotics correctly. METHODS Secretion bacteriology and bacterial sensitivity were detected for therapy in trauma patients with wounds from 1996 to 2000. The antibiotics resistance were examined. RESULTS A total of 2 396 strains in 3 545 cases times from wounds were isolated, the positive rate is 67.59%, the first five common strains were Staphylococcus aureus, S. epidermidis, Pseudomonas aeruginosa, Enterococcus, and Escherichia coli. The resistance rate to common antibiotics of S. aureus was ≥ 80%, imipenem/cilastatin (Tienam) and vancomycin was still effective to the G + cocci. G - bacteria had higher resistance against the 3rd generation of cephalosporins. CONCLUSIONS The bacteriology and the surveillance of antibiotics resistance are important to using antibiotics reasonably.

关 键 词：创伤 伤口感染 病原菌 抗生素 选择 耐药性 

分 类 号：R641[医药卫生—外科学] R978.1[医药卫生—临床医学]