The Effects of Exogenous Nitric Oxide on Eimeria tenella Oocysts  

作　　者：LIJin－gui ZHUBei－lei JIANGJin－shu 

机构地区：[1]CollegeofAnimalHusbandryandVeterinaryMedicine,YangzhouUniversity,Yangzhou225009,P.R.China [2]CollegeofVeterinaryMedicine,ChinaAgriculturalUniversity,Beijing100094,P.R.China

出　　处：《Agricultural Sciences in China》2003年第1期91-97,共7页中国农业科学（英文版）

基　　金：The study was supported by National Natural Science Foundation of China(39970564).

摘　　要：The effects of exogenous NO on Eimeria tenella oocysts were studied. The E. tenella oocysts freshly isolated from feces of experimental chickens infected with E. tenella and sporulated E. tenella oocysts were treated in vitro by the well-known NO-donors, SNP, SPER/NO and GSNO. The results showed that among the 3 NO donors, only GSNO had significant effects on the percentage of sporulated oocysts, the inhibiting rate of purified oocysts was from 93 to 97%, and reached 100% on the oocysts in the feces of chickens with E. tenella infection. GSNO also significantly decreased the virulence of E. tenella oocysts, and the oocysts treated by 2 - 8 mmol L-1 GSNO almost lost their pathogenicity to chickens.The effects of exogenous NO on Eimeria tenella oocysts were studied. The E. tenella oocysts freshly isolated from feces of experimental chickens infected with E. tenella and sporulated E. tenella oocysts were treated in vitro by the well-known NO-donors, SNP, SPER/NO and GSNO. The results showed that among the 3 NO donors, only GSNO had significant effects on the percentage of sporulated oocysts, the inhibiting rate of purified oocysts was from 93 to 97%, and reached 100% on the oocysts in the feces of chickens with E. tenella infection. GSNO also significantly decreased the virulence of E. tenella oocysts, and the oocysts treated by 2 - 8 mmol L-1 GSNO almost lost their pathogenicity to chickens.

关 键 词：SNP SPER/NO GSNO Eimeria tenella CHICKEN 

分 类 号：S858.315.9[农业科学—临床兽医学]