蓝光治疗对新生儿溶血病脑干听觉诱发电位的影响  

The changes of brain-stem auditory evoked response in neonatal hemolytic disease with phototherapy

作　　者：李安琪[1] 陈彦[1] 黄慧君[1] 刘小红[1] 

机构地区：[1]深圳市儿童医院,广东深圳518026

出　　处：《小儿急救医学》2003年第1期22-23,共2页Pediatric Emergency Medicine

摘　　要：目的　 探讨蓝光治疗在降低新生儿溶血病患儿的血清胆红素浓度时能否逆转脑干听觉诱发电位结果的改变。 方法 　对 2 0例新生儿ABO血型不和溶血病引起的高胆红素血症患儿光疗前后进行脑干听觉诱发电位检测 ,并与 2 2例正常新生儿作对照。 结果 　光疗后随着胆红素浓度的下降 ,新生儿溶血病患儿脑干听觉诱发电位值V波潜伏期 ,Ⅲ Ⅴ ,Ⅰ Ⅴ波间期较光疗前明显缩短 (P <0 0 1)。 结论 　光疗不仅能降低血清胆红素浓度 ,而且能逆转胆红素对脑干听觉诱发电位的影响 。Objective To study the changes and the effections of brain stem evoked response in neonatal hemolytic disease treated with phototherapy.Methods brain stem auditory evoked response before and after phototherapy were compared in 20 new borns of hemolytic disease with hyperbilirubinemia,22 normal newborns were tested as controls.Results Bilirubinemia levels after phototherapy were declined.The latencies of peak V and interpeaks 即Ⅲ Ⅴ,Ⅰ Ⅴ of the brain stem auditory evoked response were significantly shorter than that before phototherapy ( P <0 01).Conclusion Phototherapy can decline significantly bilirubin levels,and improve brain stem auditory evoked response.These findings demonstrated that the bilirubin encephalopathy can be improved after phototherapy.

关 键 词：蓝光治疗 新生儿 溶血病 脑干听觉诱发电位 高胆红素血症 

分 类 号：R722.18[医药卫生—儿科] R722.17[医药卫生—临床医学]