初孕年龄与妊娠期糖尿病发病率关系的流行病学研究  

Epidemiological Study on the Relationship between the First Gestational Age and the Prevalence of Gestational Diabetes Mellitus(GDM)

作　　者：赵伟[1] 王建华[1] 苗汝娟[1] 

机构地区：[1]天津医科大学公共卫生学院,天津300070

出　　处：《中国慢性病预防与控制》2003年第1期5-6,18,共3页Chinese Journal of Prevention and Control of Chronic Diseases

基　　金：国家自然科学基金资助 (39970 661 )

摘　　要：目的探讨初孕年龄与妊娠期糖尿病发病率的关系。方法通过问卷获得研究对象的人口统计学特征、既往疾病史、孕产史 ;通过测量获得身高、体重、5 0 g GCT1h血糖、75 g OGTT空腹血糖、2 h血糖等。统计方法采用非条件 L o-gistic回归分析。结果单因素回归分析显示 :经产史 (RR=8.5 16 6 ,95 % CI1.6 5 5 2～ 4 3.82 0 4 )、既往多囊卵巢综合征(RR=32 .2 6 34,95 % CI1.92 5 0～ 5 39.6 382 )、初孕年龄 (RR=3.4 0 80 ,95 % CI1.5 2 5 4～ 7.6 139)增加孕妇发生妊娠期糖尿病 (GDM)的危险 ;多因素分析表明 :只有初孕年龄与 GDM有关联。结论初孕年龄是 GDM的独立危险因素。Objective In order to explore the relationship between the first gestational age and the prevalence rate of GDM.Methods Demographic characteristics,history of diseases,past obstetric history of the subjects were investigated with questionnaire.Body height,weight,and levels of 50 g 1 hour blood glucose,75 g GTT FBS and 2 hour blood glucose were measured.Relative risks and 95% confidence intervals were calculated by means of non conditional Logistic regression.Results The risk for GDM increased significantly with the factors of past parity ( RR =8 516 6,95%CI 1 655 2～43 820 4),polycystic ovary syndrome(PCOS)( RR =32 263 4,95%CI 1 925 0～539 638 2) and the first gestational age( RR =3 400,95%CI 1 525 4～7 613 9).The non conditional Logistic regression covariate analysis showed that only the first gestational age was a independent risk factor for GDM.Conclusion The occurrence of GDM was related to the first gestational age.\;

关 键 词：初孕年龄 妊娠期 糖尿病 发病率 流行病学 研究 

分 类 号：R714.256[医药卫生—妇产科学] R587.101[医药卫生—临床医学]