鼻病毒感染与儿童哮喘发作关系探讨  

A study on the correlation of rhinovirus virus infections with asthma exacerbation in infants

作　　者：邹映雪[1] 鲁继荣[1] 刘丽[1] 成换吉[1] 刘文东[1] 周亮[1] 康淑英[1] 

机构地区：[1]吉林大学第一医院儿科,吉林长春130021

出　　处：《吉林医学》2003年第2期120-121,共2页Jilin Medical Journal

摘　　要：目的:探讨儿童哮喘发作与鼻病毒感染的关系。方法:采用逆转录聚合酶链反应(RT-PCR)方法对72例哮喘发作期患儿进行鼻病毒(RV)检测,并进行不同年龄组病原分布情况比较,同时设立健康对照组。结果:72例哮喘发作期患儿中检出RV阳性病例29例(27.8%),与健康对照组相比差异有显著性;3岁以上年龄组RV感染率为51.9%(27/52),明显高于3岁以下组,两者差异有显著性。结论:小儿哮喘发作与RV感染密切相关,RSV是诱发3岁以上哮喘发作的主要因素。Objective To explore the relationship of rhinovirus(RV)with asthma exacerbation in children.Method To detect the RV frequently irritate acute respiratory tract infection in children in72cases with asthma exacerbation by reverse tran-scription-PCR(RT-PCR).Results Evidence of RV were obtained in29cases(27.8%)of the group of asthma exacerbation,in the group of >3years,27cases were found positive(51.9%),a significant difference was found in the two groups of different ages.Conclusion27.8%of the asthma attacks in children were precipitated by acute RV infections,the ratio in>3years was51.9%,RV was the most common agent in asthma exacerbation of >3years.

关 键 词：儿童 哮喘 鼻病毒感染 逆转录聚合酶链反应 

分 类 号：R725.6[医药卫生—儿科]