上颌窦后鼻孔息肉组织病理学研究  

A study on the histopathology of antrochoanal polyp

作　　者：李长青[1] 金春顺[1] 文莲姬[1] 李刚[2] 

机构地区：[1]吉林大学第二医院耳鼻喉科,吉林长春130021 [2]磐石市医院五官科,吉林磐石132300

出　　处：《吉林医学》2003年第2期136-137,共2页Jilin Medical Journal

摘　　要：目的:研究上颌窦后鼻孔息肉(Antrochoanalpolyp,ACP)的组织病理学特点。方法:采用HE、AB-PAS染色对96例上颌窦后鼻孔息肉患者的上颌窦后息肉及320例鼻息肉(Nasalpolyp,NP)患者的息肉组织进行观察。结果:在96例上颌窦后鼻孔息肉患者中观察到鳞状上皮化生的例数明显高于鼻息肉患者(P<0.01);而观察到杯状细胞化生、嗜酸性细胞浸润、黏膜下腺体的例数明显低于鼻息肉患者(P<0.01);在病理分型方面,ACP组纤维型占明显优势;NP组浸润型占明显优势(P<0.01);结论:ACP是从呼吸道上皮水肿肥厚而来,而不是由腺体结构膨胀而来。ACP形成与变态反应关系不大,较多偏重炎性过程。Objective To compare the histopathological characteristics of 96cases of antrochoanal polyp(ACP)with those of ordinary nasal polyp (NP0,and so possikly to elncidate the pathogenesis of ACP and the differences between ACP and NP.Method To observe samples by HE and AB-PAS staining.Re sults Yuamous cell metaplasia was significantly more severe in the ACP group than that in the NP group.Goblet cell metaplasia and Eosinophilic infiltration were significantly less severe in the ACP than those in the NP.The fibrous type was present significantly more often than the infiltrative type in the ACP group.Con clu sion The histopathologic findings of the ACP suggest that it has little causal relationship with nasal allergy,but is all the more intimately associated with inflammatory processes.

关 键 词：上颌窦后鼻孔息肉 组织病理学 HE染色 AB-PAS染色 光学显微镜 发病机制 

分 类 号：R765.25[医药卫生—耳鼻咽喉科]