大鼠睾丸微血管变化的定量研究  

The quantificational study of testicular tiny blood vessels changes in rats

作　　者：康友敏[1] 张健[1] 段相林[1] 

机构地区：[1]河北师范大学生命科学学院动物细胞生物学研究室,河北石家庄050016

出　　处：《中国老年学杂志》2003年第4期252-254,共3页Chinese Journal of Gerontology

基　　金：河北省自然科学基金资助项目 (30 0 1 64)

摘　　要：目的　探讨大鼠睾丸微血管的增龄变化及其对睾丸功能的影响。方法　采用石蜡切片及 HE染色法 ,对睾丸微血管进行定量测定。结果　随着增龄变化 ,微血管管壁的平均厚度呈增大趋势 ;从初生到 2月龄每个生精小管周围的微血管数目不断增加 ,到 6月龄略减少 ,1 2月龄至2 4月龄微血管数量呈减少趋势 ;单位面积内微血管数目与生精小管数目的比值从初生到 6月龄增至最大值 ,到 2 4月龄比值呈减小趋势。结论　微血管管壁厚度与微血管数目变化是睾丸衰老的重要原因。Objective The purpose of this study is to discuss the effects of testicular tiny blood vessels changes on the function of testis in rats.Methods The testis tissue were embedded in paraffin and counterstained with hematoxylin to measure the tiny blood vessels.Results The average thickness of tiny blood vessel walls are increased with aging.The numbers of tiny blood vessels around every seminiferous tube are increased from birth to 2 month postnatal and decreased on 6 month postnatal,while there is a decrease tendency from 12 month postnatal to 24 month postnatal.The ratio of numbers of tiny blood vessels to numbers of seminiferous tubes reach the maximum on 6 month postnatal and decrease on 24 month postnatal. Conclusions The thickness of tiny blood vessel walls and numbers of tiny blood vessels are important reasons for testis aging.

关 键 词：睾丸 微血管变化 睾丸功能 增龄变化 定量测定 微血管管壁 平均厚度 

分 类 号：R697.22[医药卫生—泌尿科学]