纳米羟基磷灰石的常压合成与表征  

The Synthesis at Normal Atmospheric Pressure and Characterization of Nano Hydroxyapatite Crystals

作　　者：左奕[1] 李玉宝[1] 魏杰[1] 严永刚[1] 

机构地区：[1]四川大学纳米生物材料研究中心四川大学分析测试中心,成都610064

出　　处：《高技术通讯》2003年第4期58-61,共4页Chinese High Technology Letters

基　　金：国家自然科学基金(30270399)资助项目。

摘　　要：以乙二醇为氢氧化钙的溶剂在常压下合成了一种纳米羟基磷灰石晶体。分析结果表明,以乙二醇为氢氧化钙(Ca(OH)2)的溶剂反应合成的羟基磷灰石为细针状的纳米晶体,具有弱结晶结构,为非化学计量,其钙磷摩尔比约为1.66。这种纳米磷灰石晶体和自然骨中的磷灰石晶体在很多方面有相似之处。A new method that calcium hydroxide (Ca(OH)2) with ethylene glycol as solvent reacts with orthophos-phoric acid (H3PO4) is investigated. The research shows that ethylene glycol is a good solvent for calcium hydroxide to prepare the needle-like nano hydroxyapatite (n-HA)crystals. The n-HA has a poor crystallization and is non-stoichiometry with a Ca/P molar ratio of 1.66. This calcium-def icent n-HA is similar to the natural bone apatite in many aspects like composition, morphology, crystallinity.

关 键 词：纳米羟基磷灰石 常压 人工合成 结构表征 生物材料 针状晶体 非化学计量 

分 类 号：R318.08[医药卫生—生物医学工程] TB383[医药卫生—基础医学]