输精管绝育术与肺癌死亡率的关系  

VASECTOMY AND LUNG CANCER MORTALITY

作　　者：左惠娟[1] 车锡嘏[2] 张思霖[3] 陈彬[2] 王安荣[4] 黄强[3] 邹平[3] 秦健[3] 

机构地区：[1]北京心肺血管疾病研究所,100029 [2]华西医科大学 [3]四川省计划生育科学研究所 [4]四川省肿瘤研究所

出　　处：《现代预防医学》2003年第2期151-153,共3页Modern Preventive Medicine

摘　　要：目的 :探讨输精管绝育术与肺癌的关系。方法 :对盐亭县 40～ 70岁男性进行三年回顾及两年随访调查 ,及队列内 1∶ 2肺癌病例对照研究。采用 Poisson回归及条件 Logistic回归进行资料进行分析。结果 :绝育人群中 ,绝育不足 10年者肺癌死亡危险明显低于绝育 2 0年以上者 RR=0 .17(95 % CI:0 .3 4～ 0 .85 ) ,随着绝育时年龄的增加肺癌死亡危险增加 ,和40岁后绝育者相比 3 0～ 3 9岁、 3 0岁以前绝育者相对危险分别为 0 .83 (95 % CI:0 .0 2～ 0 .3 6)、 0 .16(95 % CI:0 .0 8～0 .3 4)。 1∶ 2病历对照研究发现绝育年限、绝育时年龄对肺癌死亡无影响。结论 :肺癌死亡率在绝育人群和未绝育人群间差异无显著性 。Objective:In order to evaluate the relationship of vasectomy and lung cancer Mortality Methods:Men aged from 40 to 70 were investigated by historic al prospective study of a three-year retrospective investigation once and two year s follow-up,1∶2 case control study was matched The risk was evaluate d using Poisson and Conditional Logistic regression analys is Results:The mortality of lung cancer in the men whose history of v asectomy was less than 1 0 years was significantly lower than that of whose history of vasectomy was mo re than 20 years, relative risk (RR) was 0 17, 95%CI(0 34～0 85), the relative r isks i ncreased with the age growing of vasectomy Compared with the men who sterilize d after 40 years old, the relative risks of the men sterilized before 30 years ol d and from 30 to 39 years old were 0 83 and 0 16,95% confidence interva l wa s 0 02～0 36, and 0 08～0 34,respectively The result from 1∶2 case contro l stud y showed there was no significant relation between vasectomy and the mortality o f lung cancer Conclusion:There was not difference between vasectomi ed men and non-vasectom ied men on the morality of lung cancer, but it could be decreased sterilized in ones early age

关 键 词：输精管绝育术 肺癌 Poisson回归分析 条件LOGISTIC回归分析 

分 类 号：R181.32[医药卫生—流行病学]