升麻地上部分新的三萜皂苷类成分  

Studies on the New Triterpenoid Saponin of the Aerial Part of Cimifuga foetida

作　　者：潘瑞乐[1] 陈迪华[1] 斯建勇[1] 赵晓宏[1] 沈连钢[1] 

机构地区：[1]中国医学科学院中国协和医科大学药用植物研究所,北京100094

出　　处：《中国中药杂志》2003年第3期230-232,共3页China Journal of Chinese Materia Medica

摘　　要：目的 :从升麻Cimicifugafoetida地上部分寻找新的天然活性成分。 方法 :利用多种色谱技术进行分离纯化 ,根据理化性质和现代波谱技术并辅以化学方法进行结构鉴定。结果 :从升麻地上部分 80 %乙醇提取物的乙酸乙酯部分分得 4个 9,19 环菠萝蜜烷型三萜皂苷 ,分别鉴定为 :西麻苷Ⅲ (1) ;2 5 O 乙酰升麻醇木糖苷 (2 ) ;2 5 O 乙酰升麻醇半乳糖苷 (3) ;7β 羟基升麻醇木糖苷 (4)。 结论 :1为新化合物 。Objective:To find new active constituents from the aerial part of Cimicifuga foetida . Method: Various column chromatographic techniques were used for the isolation and purification of the principles. The structures were elucidated on the basis of spectral data and chemical evidences. Result: Four 9,19 cycloartane triterpenoid saponins were obtained and identified as Cimifoetiside Ⅲ (25 anhydrocimigenol 3 O β D galactopyranoside, 1), 25 O acetyl cimigenol xylopyranoside (2), 25 O acetyl cimigenol galactopyranoside (3), 7β hydrocimigenol xylopyranoside (4). Conclusion: Compound 1 is new and compound 4 was isolated from this plant for the first time.

关 键 词：毛莨科 升麻地上部分 两麻苷Ⅲ 

分 类 号：R284.1[医药卫生—中药学]