沙漠热环境负重行军对淋巴细胞HSP70的影响  

Effects of marching with load of 1.5 kilograms in dry-heat desert on heat shock protein 70 in human lymphocyte

作　　者：刘兵[1] 邬堂春[2] 陈胜[2] 吴志豪[1] 徐文[1] 张雪玲[1] 

机构地区：[1]兰州军区联勤部军事医学研究所,兰州730020 [2]华中科技大学同济医学院职业医学研究所

出　　处：《中国公共卫生》2003年第4期396-397,共2页Chinese Journal of Public Health

基　　金：全军青年基金 (96Q0 2 2 )资助课题

摘　　要：目的　探讨沙漠热环境负重行军者血淋巴细胞HSP70的变化规律。方法　对沙漠干热环境中以不同速度和时间负重行军的 5 4名战士和 14名对照者血淋巴细胞HSP70进行对比分析。结果　相同行军时间的不同行军速度间淋巴细胞HSP70有显著性差异 (P <0 0 5 ) ;3 5km/h行军 3h组淋巴细胞HSP70明显高于对照和行军 2h组 (P <0 0 5 ) :5 0km/h行军 1 2h组血淋巴细胞HSP70明显高于对照和行军 3h组 (P <0 0 5 )。结论　随行军速度和时间的增加 ,淋巴细胞HSP70增高 ;当行军速度和时间达到一定水平后 ,机体淋巴细胞HSP70明显增加。血淋巴细胞HSP70作为热损伤和热耐受的监测指标较血浆HSP70敏感。Objective To explore the regulation of heat shock protein 70(HSP70) in human lymphocyte in case of marching without load in dry-heat desert.Methods The lymphocyte HSP70 of 54 marchers at different speed at different time and 14 controls were detected.Results There was signficant difference between different speeds at the same time( P <0 05);The lymphocyte HSP70 of group for 3 hours was obviously more than that of the control and the group for 2 hours at 3.5km/h;The level of HSP70 for 1 and 2 hours is more than the control at 5.0km/h( P <0 05),but less than for 3 hours( P <0 05).Conclusion The lymphocyte HSP70 increased with speed and time.The blood lymphocyte HSP70 was more sensitive than plasma HSP70 in the monitor of heat injure and heat tolerance.

关 键 词：沙漠 热环境 负重行军 淋巴细胞 HSP70 影响 

分 类 号：R594.1[医药卫生—内科学] R339.53[医药卫生—临床医学]