结晶法分离精制混合植物甾醇中β-谷甾醇和豆甾醇  

Separation and Purification of Stigmasterol and β-Sitosterol from Phytosterol by the Crystallization Method

作　　者：许文林[1] 黄一波[1] 钱俊红[1] 沙鸥[1] 

机构地区：[1]扬州大学化学化工学院,江苏扬州225002

出　　处：《过程工程学报》2003年第1期73-79,共7页The Chinese Journal of Process Engineering

基　　金：江苏省教育厅自然科学基金资助项目(99KJB150007); 江苏省"青蓝工程"跨世纪学术带头人基金资助项目

摘　　要：利用豆甾醇和b谷甾醇在正戊醇和环己酮中的溶解性差异以及两种甾醇在环己酮中溶解度对温度的依赖性不同,研究了以正戊醇和环己酮为溶剂,用结晶法从精制植物甾醇中分离豆甾醇和b谷甾醇的工艺方法. 实验结果表明,以环己酮为溶剂,混合植物甾醇经过3次分级结晶后,b谷甾醇含量达到87%;以环己酮或正戊醇为溶剂,通过5次重结晶后,豆甾醇含量达到92%.The separation and purification of b-sitosterol and stigmasterol from phytosterol by the crystallization method using n-pentanol and cyclohexanone as solvents were studied based on the difference of the solubilities of stigmasterol and b-sitosterol and the variation of solubility with temperature. The experimental results show that the content of b-sitosterol is more than 87% after the third fractional crystallization in cyclohexanone and the content of stigmasterol is more than 92% after the fifth crystallization in n-pentanol or cyclohexanone.

关 键 词：豆甾醇 Β-谷甾醇 分离 结晶 

分 类 号：TQ654.98[化学工程—精细化工]