老年急性心肌梗死患者血管内皮功能损害情况  

Endothelial vascular dysfunction in elderly patients with acute myocardial infarction

作　　者：徐默玲[1] 陈亚萍[1] 郑义通[1] 许静[1] 金艳[1] 黄建勤[1] 

机构地区：[1]南京医科大学附属无锡市第二人民医院心内科,214002

出　　处：《实用老年医学》2003年第1期27-28,共2页Practical Geriatrics

摘　　要：目的　探讨老年急性心肌梗死 (AMI)与非老年AMI患者血管内皮舒张功能损害情况及差异。　 方法　应用高分辨的血管外超声法检测 14 8例老年AMI、非老年AMI、老年健康者、非老年健康者肱动脉血管内皮功能。　 结果　基础血管内径老年和非老年AMI组较老年和非老年健康对照组差异有显著性 (P <0 0 1) ,硝酸甘油含化后血管内径扩张百分率AMI组差于健康组 (P <0 0 1～ 0 0 5 ) ,老年组差于非老年组 (P <0 0 5 )。　 结论　老年和非老年AMI患者均存在血管内皮功能的损害 。Objective To investigate endothelial vasodilator function and difference in elderly and non elderly patients with acute myocardial infarction(AMI). Methods High frequency ultrasonographic imaging of the brachial artery was used to assess vascular endothelium function in 148 cases which were divided into 4 groups:elderly patients with AMI,non elderly patients with AMI,elderly normal persons and non elderly normal persons. Results There was significant difference between elderly patients and elderly normal persons,between non elderly patients and non elderly normal persons.The dilation rate of vascular diameter was lower in patients with AMI than that in normal persons,lower in the elderly than in the non elderly. Conclusions All patients have endothelial vasodilator dysfunction,but it is more severe in elderly than in non elderly patients.

关 键 词：急性心肌梗死 超声 内皮功能 老年人 

分 类 号：R542.22[医药卫生—心血管疾病]