地菍多糖MD_1清除活性氧自由基及对人红细胞膜脂质过氧化作用影响的研究  

Effects of Polysacharide MD_1 on Eliminating O_2^(-·) 、·OH and Anti-Peroxidation upon Human Erythrocyte Membrane

作　　者：张超[1] 姚惠珍[1] 徐兰琴[1] 杨凤仪[1] 方岩雄[2] 

机构地区：[1]广州医学院基础部,广州510182 [2]广东工业大学轻化学院,广州510090

出　　处：《广州医学院学报》2002年第4期18-20,24,共4页Academic Journal of Guangzhou Medical College

摘　　要：Objective:To investigate the effects of polysacharide MD 1 on eliminating free radical O -· 2,·OH and anti peroxidation on human erythrocyte membrane. Methods:testing the effect of eliminating O -· 2?·OH of MD 1 at different concentrations in vitro;testing the influence of MD 1 on peroxidation of free radical of human erythrocyte membrane by fluorescence. Results:Polyssacharide MD 1 could eliminate O -· 2 and·OH(<250 mg/L).compared with the control group( P <0.01). The result also showed that MD 1 could inhibit lipid peroxidation of human erythrocyte membrane,compared with the control group( P <0.01).Objective:To investigate the effects of polysacharide MD 1 on eliminating free radical O -· 2,·OH and anti peroxidation on human erythrocyte membrane. Methods:testing the effect of eliminating O -· 2?·OH of MD 1 at different concentrations in vitro;testing the influence of MD 1 on peroxidation of free radical of human erythrocyte membrane by fluorescence. Results:Polyssacharide MD 1 could eliminate O -· 2 and·OH(<250 mg/L).compared with the control group( P <0.01). The result also showed that MD 1 could inhibit lipid peroxidation of human erythrocyte membrane,compared with the control group( P <0.01).

关 键 词：地芩多糖 MD1 活性自由基 人红细胞膜 脂质过氧化作用 影响 研究 

分 类 号：R285.1[医药卫生—中药学]