慢性肺原性心脏病急性发作期止凝血过程异常的实验研究  

An Experimental Research on the Disorders of Hemostasis-Coagulation Process During the Acute Stage of Chronic Pulmonary Heart Disease(CPHD)

作　　者：徐玉清[1] 王孟学[1] 周志健[1] 洪宝源 杨柏林[2] 姚臣[2] 

机构地区：[1]哈尔滨医科大学二院血液内科 [2]哈尔滨医科大学二院呼吸内科

出　　处：《哈尔滨医科大学学报》1992年第2期102-105,共4页Journal of Harbin Medical University

摘　　要：本文对42例慢性肺心病急性发作期患者进行了多指标的止凝血状态的检测,发现病人在止凝血过程的各个环节,包括血管内皮、凝血系统、抗凝及纤溶系统、血小板功能、血液流变学等方面均有明显异常。分析结果表明,肺心病急性发作期存在着严重的止凝血功能紊乱,血栓形成倾向是异常的主要方面。A systematic multi-indices detecting has been made on 42 patients with chronic pulmonary heart disease (CPHD)during the acute stage and significant disorders have been found in every link of hemostasis-coagulation process including vascular endothelial cells, coagulation system, anticoagulation and fibrinolysis system, platelet function, hemorrheology etc. The results of analysis showed: There is serious disorder of hemostasis-coagulation process during the acute stage in CPHD and the thrombokinesis tendency is its main process. The hypercoagulation state and hyperviscosity of blood coexist and the interaction between them may play an important role in thrombokinesis.

关 键 词：止凝血 血栓形成 肺心病 

分 类 号：R541.502[医药卫生—心血管疾病]