盐酸氟西汀对原发性高血压伴抑郁症患者血压影响的临床观察  

Clinical Observation of Blood Pressure Change in Patients with Primary Hypertension and Depression Treated by PROZAC

作　　者：程文立[1] 张红[1] 杜宏举[1] 吴继全[1] 

机构地区：[1]北京中日友好医院,100029

出　　处：《医学研究通讯》2003年第4期38-39,共2页Bulletin of Medical Research

摘　　要：目的观察盐酸氟西汀抗抑郁治疗对原发性高血压伴抑郁症患者血压的影响。方法将原发性高血压伴抑郁症患者(82例)随机分为盐酸氟西汀组及一般治疗组,盐酸氟西汀组给予盐酸氟西汀20mg每日一次治疗及降压治疗,一般组仅予以降压药治疗,共观察8周,对患者血压及Zung量表积分进行评定。结果盐酸氟西汀组治疗后患者Zung量表积分与治疗前比较有显著下降(P<0.01),患者的收缩压及舒张压与治疗前比较也有显著下降(P<0.05)。一般治疗组患者疗前疗后患者收缩压、舒张压及Zung量表积分均无明显变化。结论抗抑郁治疗有助于原发性高血压伴抑郁症患者的血压控制。Objective To observe weather the anti - depression therapy by using PROZAC has beneficial effection on patients with primary hypertension and depression.Methods The 82 patients were classified into two classes randomly.One was given PROZAC and normal hypotensor, the other was only given normal hypotensor. We had observed 8 weeks, during the course, we examined the patient' s blood pressure and Zung scores at the Second week, the forth week and the eighth week respectively. Results the blood pressure and the Zung scores of the group treated by PROZAC and normal hypotensor was significantly reduced after 8 weeks (P< 0.05 and P< 0.01) .The blood pressure and the Zung scores of the normal contrast group treated by normal hypotensor had not any change (P> 0.05) .

关 键 词：盐酸氟西汀 原发性高血压 抑郁症 患者 血压 影响 临床观察 

分 类 号：R544.1[医药卫生—心血管疾病] R971.4[医药卫生—内科学]