151例神经系统疾病脑脊液β_2—微球蛋白的放射免疫测定  

Radioimmunoassay of Cerebrospinal Fluid β_2 microglobulin in 151 Patients with the Diseases of Nervous System

作　　者：邢永前[1] 巫志明[1] 陈富嫦[1] 许志恩[1] 潘儒南 邹劲[1] 张俊徽[1] 凌蓓蒂[1] 周伟正[1] 薛瑶嫦 莫凡[1] 

机构地区：[1]湛江医学院附属医院

出　　处：《海南医学》1992年第1期25-28,共4页Hainan Medical Journal

摘　　要：本文用放免法测定151例神经疾患病人和21例正常人CSF中β_2-微球蛋白含量。病变组包括急性脑血管病、颅内感染性疾病、脊髓疾病、症状性癫痫和其他疾病。正常组均值为1.21Ug/ml。病变组均值普遍增高,与正常组对比均有显著性差异,但以出血性脑血管病、细菌或真菌性脑膜炎和脊髓压迫症者升高尤为显著。资料表明CSF中β_2-微球蛋白不适于做为特异性诊断指标,但对于同一组疾病中的各个病种之间的鉴别有一定的意义,The concentration of CSF microglobulin (m) was determinated in 151 patients with nervous system diseases including acute cerebrovascular diseases, intracra-nial infections, spinal cord diseases, symptomatic epilepsy and others. The mean level of CSF (m in normal control was 1.21ug/rnl. m level of csf in patients with each group is significantly higher than that of the control, especially in the patients with luanorrh-agic cerebrovascular diseases, meningitis of bacteria or mycotic organism and compressive myelopat-hy. The result showed that the increasing level of CSF m is not a specific diagnostic index, yet it is of some value in the differential diagnosis between hemorrhagic and ischemic cerebrovascular diseases, bacteria and aseptic intracranial diseases,compressive and noncomp-ressive myelopathy.

关 键 词：脑脊液 Β2-微球蛋白 放射免疫分析 

分 类 号：R446.14[医药卫生—诊断学]