大环多胺配体ODTH的合成及其性质的研究  

Studies on the Synthesis and Character of the Macrocylic Polyamine ODTH

作　　者：迟姚玲[1] 王吉德[1] 岳凡[1] 陈玲[1] 

机构地区：[1]新疆大学化学化工学院,乌鲁木齐830046

出　　处：《无机化学学报》2003年第5期557-560,共4页Chinese Journal of Inorganic Chemistry

基　　金：教育部骨干教师计划资助项目。

摘　　要：A new dinucleating 36 membered octoazadiphenol macrocyclic ligand, 3,6,9,12,20,23,26,29 octoaza 35,36 dihydroxy 16,33 dimethyl tricyclo hexatriacontane 1(34),14,16,18(36),31,32 hexene, ODTH, was synthesized by NaBH4 hydrogenation of the corresponding Schiff base obtained from the condensation between triethylenetetraamine and diformyl p cresol. It was characterized by elemental analysis, IR, UV Vis, 1H NMR and MS. The protonation constants of ODTH and the stability constants of its complexes with Cu?in 1∶1 and 1∶2 system(metal ODTH), have been determined potentiometrically at 25.0℃and μ=0.100 mol·L-1 KCl. Potentiometric equilibrium studies indicate that a variety of deprotonated and protonated mononuclear and dinuclear, as well as hydroxy bridged complexes, form in the pH range 2～12 in aqueous solution. The species distributions and the characteristics of ODTH and the complexes are also described.A new dinucleating 36 membered octoazadiphenol macrocyclic ligand, 3,6,9,12,20,23,26,29 octoaza 35,36 dihydroxy 16,33 dimethyl tricyclo hexatriacontane 1(34),14,16,18(36),31,32 hexene, ODTH, was synthesized by NaBH4 hydrogenation of the corresponding Schiff base obtained from the condensation between triethylenetetraamine and diformyl p cresol. It was characterized by elemental analysis, IR, UV Vis, 1H NMR and MS. The protonation constants of ODTH and the stability constants of its complexes with Cu?in 1∶1 and 1∶2 system(metal ODTH), have been determined potentiometrically at 25.0℃and μ=0.100 mol·L-1 KCl. Potentiometric equilibrium studies indicate that a variety of deprotonated and protonated mononuclear and dinuclear, as well as hydroxy bridged complexes, form in the pH range 2～12 in aqueous solution. The species distributions and the characteristics of ODTH and the complexes are also described.

关 键 词：大环多胺配体 0DTH 合成 电位滴定 质子化常数 稳定常数 金属酶 人工酶 

分 类 号：Q55[生物学—生物化学]