丹参酮胶囊治疗结节囊肿性痤疮的临床疗效评价  

Clinical efficacy of daniston danshentong capsule in treatment of patie nts with nodular-cystic acne

作　　者：姚春海[1] 苏爱华[1] 

机构地区：[1]中国中医研究院西苑医院皮肤科,北京100091

出　　处：《中国临床药理学与治疗学》2003年第3期339-340,共2页Chinese Journal of Clinical Pharmacology and Therapeutics

摘　　要：目的 :观察丹参酮治疗结节囊肿性痤疮的临床疗效。方法 :选择符合标准的一组患者 (共 3 5例 ,3 1例完成观察 ) ,口服丹参酮胶囊 (0 .2 5g 粒 ) ,每次4粒 ,每日 3次 ,连服 8wk后 ,改为每次 3粒 ,每日 3次 ,总疗程共 1 2wk。结果 :治疗的总有效率为83 .9% ,治疗 2、4、8、1 2wk后结节囊肿性皮损平均数目分别是 1 9± 9、1 5±6、1 0±6和 7± 7(P <0 .0 1 ) ,与治疗前 (2 3±1 1 )比较 ,P <0 .0 1。结论 :丹参酮对结节囊肿性痤疮有较好的临床疗效 。AIM: To observe the clinical effects of daniston danshentong c apsule in treatment of patients with nodular-cystic acne. METHODS: A group of patients (31 cases finished their observation in all 35 cases) wa s selected to take daniston danshentong capsule ( 0.25 g/capsule), 4 capsules three times daily. After continuous taking the agent for 8 weeks, the dosage ch anged to be 3 capsules three times daily. The treatment lasted for 12 weeks. RESULTS: The total effective rate was 83.9 %. Compared the mean number of the nodular-cystic acne before treatment (23±11) with that after 2 weeks of treatment (19±9), after 4 weeks (15±6), after 8 weeks (9±6), and aft er 12 weeks (7±7), all of the P values were less than 0.01 . The effective rate increased gradually along with administration time lengtheni ng. CONCLUSION: Daniston danshentong capsule is effective in tre atment of nodular-cystic acne, and eight-week course is a suitable for the tre atment.

关 键 词：丹参酮胶囊 治疗 结节囊肿性痤疮 临床疗效 不良反应 药效学 

分 类 号：R285.6[医药卫生—中药学] R275.987.33[医药卫生—中医学]