针刺足三里穴中枢作用机制的研究  

Central modulating mechanisms of ST_(36) (Zusanli) acupunctured with PET

作　　者：金香兰[1] 尹岭[1] 姚斌[1] 尹大一[1] 姚树林[1] 邵明哲[1] 单保慈[2] 唐一源[3] 朱克[1] 

机构地区：[1]解放军总医院,北京市100853 [2]中国科学院高能物理研究所,北京市100080 [3]解放军第210医院,北京市116023

出　　处：《中国康复理论与实践》2003年第3期184-186,共3页Chinese Journal of Rehabilitation Theory and Practice

基　　金：.国家自然科学基金资助项目 (30 1 71 1 35) ;国家科技部基础研究重大项目前期研究专项 (2 0 0 1CCA0 0 70 0 )

摘　　要：目的探讨针灸足三里穴的中枢作用机制。方法利用正电子发射断层摄影术 (PET)对 6例男性健康志愿者行针刺右侧足三里1 8FDG PFT脑功能成像检查 ,获得脑内葡萄糖代谢变化的实验数据 ,利用SPM软件进行统计学处理 ,获得脑功能变化的可视性实验依据。结果针刺右侧足三里可以引起同侧视丘下部、延髓背侧 ,双侧岛叶 ,对侧旁中央小叶、中央前、后回上部、额叶及颞叶的岛盖部、扣带回中部、尾状核头部、中脑和桥脑背侧中部、小脑深部葡萄糖代谢率增加 ,同侧中央前、后回上部及小脑前叶外侧部葡萄糖代谢率减低。结论针刺足三里的作用机制是通过皮层及皮层下内脏神经中枢的神经内分泌网络调节机制来实现的。ObjectiveTo discuss the central modulating mechanisms while acupuncturing the Stomach 36[ST 36 (Zusanli)]by brain functional imaging with positron emission tomography (PET).MethodsPET imaging of whole brain was performed in a group of six healthy subjects during two stimulation paradigms: pseudo acupuncture and real acupuncture at acupoint ST 36 (Zusanli). The data on cerebral glycometabolism,obtained by using PET,was analyzed by using statistical parametric mapping (SPM).ResultsThere was certain increase of glycometabolism in ipsilateral hypothalamus,back of medulla oblongata;bilateral insular lobe; contralateral paracentral lobule,superior part of precentral and postcentral gyrus,opercular part of frontal and temporal lobe,middle part of cingulate gyrus,head of caudate nucleus,middle part of the back of midbrain and pons,and deep part of cerebellum,whereas decrease in ipsilateral superior part of precentral and postcentral gyrus and lateral part of ipsilateral anterior cerebellar lobe,while acupuncturing at acupoint ST 36 (Zusanli on the right leg).ConclusionsThe central modulating mechanisms of acupuncturing ST 36 are realized by neural and neuroendocrine network modulation mechanisms of vegetative nerve center in cortex and subcortex.

关 键 词：针灸 足三里穴 正电子发射断层摄影术 脑 

分 类 号：R245.0[医药卫生—针灸推拿学]