灵芝颗粒剂对小鼠镇静催眠和免疫功能的影响  

Effects of Ganoderma Lucidum Granules on Sedation, Hypnosis and Immune Function in Mice

作　　者：寿文虹 龚彬荣 方远书 何忠平 

机构地区：[1]浙江省金华市药品检验所,浙江金华321000

出　　处：《中国药业》2003年第3期42-43,共2页China Pharmaceuticals

摘　　要：目的:观察灵芝颗粒剂的镇静催眠、增强免疫功能作用。方法:采用开阔法、戊巴比妥钠致小鼠睡眠时间、士的宁致小鼠惊厥法,测定小鼠脾指数、胸腺指数和白细胞数。结果:灵芝颗粒剂能明显减少小鼠自主活动,缩短戊巴比妥钠致小鼠睡眠潜伏期,延长戊巴比妥钠致小鼠睡眠时间,能对抗士的宁致小鼠惊厥的作用,能升高小鼠脾指数、胸腺指数和白细胞数。结论:灵芝颗粒剂具有镇静催眠、增强免疫功能的作用。Objective:To observe the effects of Ganoderma Lucidum Granules on the sedation, hypnosis and immune function in mice. Methods: Open field method, Sleep - promoting test in combination with pentobarbital sodium, anti -convulsant activity,determining the spleen index and chest gland index,the amount of the white blood cells(WBC). Results:It can obviously reducing the autonomic activity,and promoting sleep in combination with pentobarbital sodium, anti - convulsant activity, obviously increase the spleen index and chest gland index, the amount of the WBC. Conclusion:It has the effects of sedation, hypnosis and strengthening immune function.

关 键 词：灵芝颗粒剂 小鼠 镇静 催眠 免疫功能 影响 

分 类 号：R285.5[医药卫生—中药学]