脂麻花醇提物对S_(180)和H_(22)小鼠的抗肿瘤作用研究  

Antitumor Effect of Alcohol Extract from Sesamum indicum Flower on S180 and H22 Experimental Tumor

作　　者：许华[1] 杨晓明[1] 杨锦南[2] 齐伟[2] 刘春霞[2] 杨玉亭[2] 

机构地区：[1]暨南大学药学院医药生物技术研究开发中心,广州510632 [2]新乡医学院药理学教研室,河南新乡453000

出　　处：《中药材》2003年第4期272-273,共2页Journal of Chinese Medicinal Materials

摘　　要：目的:研究脂麻花醇提物对小鼠移植瘤的抗肿瘤作用。方法:观察脂麻花醇提物对小鼠肉瘤S_(180)和肝癌H_(22)的抗肿瘤作用,测定其对荷瘤小鼠免疫器官的影响。结果:6、3、1.5g/kg脂麻花醇提物对S_(180)和H_(22)小鼠瘤株均有明显抑制作用,但对荷瘤小鼠的胸腺指数、脾指数无明显影响。结论:脂麻花醇提物具有抗肿瘤作用,对S_(180)小鼠和H_(22)小鼠抑瘤率分别为25.2％～53.6％和27.1％～40.1％。Objective: To investigate the antineoplasm effect of extract from Sesamum indicum L flower. Method: Observing the effects of alcohol extract from Sesamum indicum flower on tumor growth in sarcoma 180 ( S180 ) and Heps 22 ( H22) tumorigenic mouse, and on weight of immune organs. Result:6,3,1.5 g/kg extract showed inhibiting effect on tumor growth obviously, and had not distinct effect on weight of thymus and spleen in mice sarcoma 180 and Heps 22. Conclusion: The alcohol extract from Sesamum indicum flower showed obvious antitumor effect.

关 键 词：脂麻花 醇提物 S180 H22 小鼠 抗肿瘤作用 荷瘤小鼠 免疫器官 实验研究 

分 类 号：R285.5[医药卫生—中药学] R73－36[医药卫生—中医学]