增生性疤痕组织与正常上皮组织FTIR光谱研究  

FTIR Study on the Hypertrophicscar and Normal Skin Tissues

作　　者：东野广智[1] 孟庆勇[1] 张培华[2] 汤少明[2] 周群[3] 孙素琴[3] 胡鑫尧[3] 

机构地区：[1]广东医学院分析中心,广东湛江524023 [2]广东医学院附属医院整形外科,广东湛江524001 [3]清华大学化学系,北京100084

出　　处：《光谱学与光谱分析》2003年第2期270-272,共3页Spectroscopy and Spectral Analysis

摘　　要：通过对40例疤痕组织和正常皮肤组织的ETIR光谱比较分析发现,由于个体差异,其光谱均可分为三种不同类型。此外,疤痕组织中的胶原、蛋白质、核酸和脂类等生物大分子的吸收峰强度均在不同程度上高于正常皮肤组织,但两者的A_(1083)/A_(1548)并无明显差异。提示疤痕组织中的细胞仍属正常生长,治疗中不应损伤。40 cases of hypertrophicscar (HS) tissues and corresponding normal skin tissues were studied by FTIR technique, and the results showed that all of the HS and normal tissues can be classified into three kinds. Furthermore, the absorption bands of biomacro-molecule in collagen, protein, nucleic acid and lipid of hypertrophicscar are stronger than those of normal tissues. But there is no significant difference in A(1 083)/A(1 548) between HS and normal tissues. It is suggested that the cells of HS could still be normally growing and should not be scathed in the treatment process.

关 键 词：增生性疤痕 疤痕组织 正常上皮组织 FTIR 傅里叶变换红外光谱法 对比分析 

分 类 号：R619.6[医药卫生—外科学] R364.3[医药卫生—临床医学]