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机构地区:[1]Department of Chemical and Biochemical Engineering,Zhejiang University [2]State Key Laboratory of Bioreactor Engineering,East China University of Science and Technology [3]Department of Chemical and Biochemical Engineerirrg,Zhejiang University
出 处:《Chinese Journal of Chemical Engineering》2003年第2期141-145,共5页中国化学工程学报(英文版)
基 金:Supported by the National Natural Science Foundation of China(No.20076042,No.20206029);and the Scientific Research Foundation of the State Education Ministry for the Returned Overseas Chinese Scholars(No.2002-247).
摘 要:Expanded bed adsorption (EBA) has been widely used in industrial downstream bioprocessing. Solid matrix is the principal pillar supporting the successful application of EBA. A novel spherical cellulose-titanium dioxide composite matrix was prepared through the method of water-in-oil suspension thermal regeneration. Its typical physical properties were wet density 1.18g.cm-3, diameters in the range of 100-300um, porosity 85.5%, and water content 72.3%. Expansion characteristics and liquid mixing performance of the matrix in expanded bed were investigated using water and 10% (by mass) glycerol solution as mobile phases. The results indicate that the custom-assembled matrix has a stable flow hydrodynamics and exhibits the same degree of liquid-phase mixing or column efficiency as the commercially available Streamline adsorbent.Expanded bed adsorption (EBA) has been widely used in industrial downstream bioprocessing,Solid matrix is the principal pillar supporting the successful application of EBA.A novel spherical ceelulose-titanium dioxide composite matrix was prepared through the method of water-in-oil suspension thermal regeneration.Its typical physical properties were wet density 1.18g.cm^-3,,diameters in the range of 100-300μm ,porosity 85.5%,and water content 72.3%.Expansion characteristics and liquid mixing performance of the matrix in expanded bed were investigated using water and 10% (by mass )glycerol solution as mobile phases,The results indicate that the custom-assembled matrix has a stable flow hydrodynamics and exhibits the same degree of liquid-phase mixing or column efficiency as the commercially available Streamline adsorbent.
关 键 词:expanded bed adsorption MATRIX CELLULOSE titanium dioxide
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