用镀金靶在回旋加速器内束流装置中生产^(199)Tl  

PREPARATION OF ^(199)TI USING THE ELECTROPLATING GOLD TARGETS ON THE INTERNAL TARGET INSTALLATION OF CYCLOTRON

作　　者：周德海[1] 谢德高[1] 曹养书[1] 廖福泉 张友发[1] 王泽赋 

机构地区：[1]四川大学原子核科学技术研究所,成都610064

出　　处：《核化学与放射化学》1992年第3期174-179,共6页Journal of Nuclear and Radiochemistry

基　　金：四川省科学技术委员会资助

摘　　要：利用回旋加速器内束流装置上引出的。粒子束流强度可达150—200μA,能量在24—25 MeV,轰击用铜为衬底的镀金靶头。发生^(197)Au(α,2n)^(199)Tl核反应,产生(199)Tl。研究了从铜、金和镓中分离铊的条件。^(199)Tl与^(200)Tl的活度分别为2.3×10~5Bq和7.1×10~2Bq,即^(200)Tl占^(199)Tl总活度的0.29％。The separative conditions of 199T1 from Cu、Au and Ga by reaction 197Au (α,2n)199Tl on the internal target installation of cyclotron is studied. The a-particle energy is selected in the range of 24-25 MeV. The cumulative current intensities of such a-particle beams bombarding the gold target at 150-200μA are 1200μA·h and 1500μA· h respectively. The radiochemical separation of 199Tl is carried out with isopropyl ether extraction and anion exchange from the irradiated gold targets. The radioactivities of 199Tl and 200Tl are 2. 3×105Bq and 7. 1×102Bq,and 200Tl makes up 0. 29% of the total radioactivity. The impurity elements contained 1ml of 199TlCl injection solution are Au<0. 2μg,Cu<0. 04μg,Fe=0. 166μg,and Ga=0. 00μg. 199TlCl has been used in clinical experiments in vivo and relatively good results have been obtained.

关 键 词：电镀金靶 ~199T1累计流强 异丙醚 

分 类 号：R981.9[医药卫生—药品]