用放射性核素体外分析法研究仙灵、地黄液的药理作用  

The pharmacological effect of Epimedium Brevicornum Maxim and Radix Rehmannial Liquid studied with in vitro radioassay

作　　者：曹茜[1] 黄吉赓[1] 宫斌[2] 方军[2] 

机构地区：[1]上海中医学院附属曙光医院,上海200021 [2]上海中医学院,上海200032

出　　处：《核技术》1992年第11期683-687,共5页Nuclear Techniques

摘　　要：动物实验表明仙灵液可提高肺-β受体含量,提高大鼠血浆及肺组织中cAMP含量;地黄液可降低大鼠血浆、肺组织中cGMP含量及降低大鼠E_2含量。两药均使cAMP/cGMP比值升高,亦可提高大鼠皮质醇含量。Epimedium Brevicornum Maxim (EBM)can increase β- receptor binding sites in lungs ofrats and raise the cAMP content and cAMP/cGMP ratio in plasma and lung of rats. ThecGMP and E2 in plasma and lung of rats were decreased and cAMP/cGMP ratio was in-. creased by Radix Rehmannial Liquid(RRL). Both drugs, EBM and RRL, can raise cortisolconcentration in plasma of rats.

关 键 词：仙灵液 地黄液 放射性同位素 药理 

分 类 号：R817[医药卫生—影像医学与核医学]