白叶莓根部化学成分的研究  被引量:9

Studies on chemical constituents from root of Rubus innominatus

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作  者:王明奎[1] 梁健[1] 彭树林[1] 丁立生[1] 

机构地区:[1]中国科学院成都生物研究所,四川成都610041

出  处:《中草药》2003年第4期295-297,共3页Chinese Traditional and Herbal Drugs

基  金:四川省青年科学基金;教育部留学回国人员科研启动基金资助

摘  要:目的 研究蔷薇科悬钩子属药用植物白叶莓 Rubus innominatus根部的化学成分。方法 用甲醇室温浸提后以乙酸乙酯萃取 ,萃取物通过多次正相和反相硅胶柱层析分离纯化 ,并采用 NMR,MS等波谱方法及与标准品对照 TL C鉴定化学结构 ,抗菌活性用杯碟法测定。结果 共分离鉴定出 10个三萜酸和 2个甾体类化合物 ,抗菌试验表明乙酸乙酯萃取物和一些三萜酸具有一定的抗菌活性。结论 这些成分均为首次从该属植物中分离得到。Object To study the chemical constituents from the root of Rubus innominatus S. Moore (Rosaceae). Methods Twelve compounds were isolated from the methanol extract by repeated column chromatography over normal and reversed phase silica gels. Their structures were identified by analysis of their spectral data and comparing TLC with authentic samples. Results Ten triterpenic acids and two steroids were isolated and identified. The antibacterial test indicated some triterpenic acids had antibacterial activity. Conclusion All compounds were obtained from the plants of Rubus L. for the first time.

关 键 词:白叶莓 根部 化学成分 研究 三萜酸 甾体类化合物 

分 类 号:R284.1[医药卫生—中药学]

 

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