恶性肿瘤医院感染影响因素的病例对照分析  

Factors Affecting the Hospital Infection in Malignant Tumor Patients: A Case-control Analysis

作　　者：夏祥碧[1] 刘力克[2] 张倩 刘亮 汪勇[5] 

机构地区：[1]四川大学望江医院,四川成都610065 [2]四川大学公共卫生学院,四川成都610041 [3]成都普济医院,四川成都610041 [4]宜宾市翠屏区卫生局,四川宜宾644000 [5]四川大学华西医院,四川成都610041

出　　处：《中华医院感染学杂志》2003年第4期315-317,共3页Chinese Journal of Nosocomiology

摘　　要：目的　了解恶性肿瘤患者的医院感染影响因素。方法　收集某医院 2 0 0 0年所有恶性肿瘤住院病例资料 ,用病例对照分析的方法 ,对可能与恶性肿瘤医院感染有关的因素进行非条件logistic回归分析。结果　多因素非条件logistic回归分析筛选出住院天数、转移、放疗、糖尿病、动静脉插管、内镜、气管切开、手术、抗生素与医院感染有关 (P均 <0 .0 1) ;按男女性别分别作logistic回归分析结果发现 :女性恶性肿瘤患者中泌尿道插管与医院感染有关 (P <0 .0 1)。结论　为减少恶性肿瘤患者医院感染的发生 ,必须重视合理使用现代医疗技术及抗生素 ,减少住院天数及不必要的侵袭性操作 ,对行化学疗法和放射疗法的患者 ,应密切监测白细胞数量 ,对伴有糖尿病的恶性肿瘤患者 ,应严格地控制血糖。OBJECTIVE To investigate the factors which influence hospital infection in the patients with malignant tumors. METHODS Collected all data from the medical records of malignant patients in 2000 in one hospital, to analyze the affecting factors with Logistic regression. RESULTS Multiple factor unconditional logistic regression screened out the relative factors: the duration in hospital, metastasis, radiotherapy, diabetes, venous catheter, bronchotomy, operation and antibiotics (P<0.01). Analyzing the factors with Logistic regression in males and females, it is found that urethral catheter is related to hospital infection in females (P<0.01). CONCLUSIONS In order to reduce the hospital infection in the patients with malignant tumors, it must be realised to reasonably use the techniques of diagnosis and treatment and antibiotics, decrease unnecessary aggressive procedures and the duration in hospital. Leucocyte must be monitored frequently in patients with chemotherapy and radiotherapy. Blood sugar should be controlled strictly in the malignant tumor patients with diabetes.

关 键 词：恶性肿瘤 医院感染 危险因素 LOGISTIC回归分析 抗生素 放疗 

分 类 号：R181.34[医药卫生—流行病学]