儿童急性呼吸道感染中流感嗜血杆菌的检测与分型  

The detection of Haemophilus influenzae on Acute respiratory infections in children

作　　者：邱景富[1] 张玉妥[1] 季建军[1] 张艳芳[1] 王晨红[1] 杨桂芬[2] 

机构地区：[1]张家口医学院微生物教研室,075000 [2]张家口医学院第一附属医院检验科,075000

出　　处：《张家口医学院学报》2003年第2期9-11,共3页

摘　　要：目的 :为了解儿童急性呼吸道感染中的流感嗜血杆菌与生物分型及其对抗生素的敏感情况。方法 :对 78例急性呼吸道感染儿童采用常规方法进行了培养 ,药敏试验与生物分型。结果 :共分离出流感嗜血杆菌 33株 ,检出率为 4 2 .3% ,在对所有分离株进行的生物分型结果中 ,共检出 5型 ,其中以Ⅳ ,Ⅵ型居多 ,分别为Ⅳ型 8例 (2 4 .2 % ) Ⅵ型 13例 (39.4 % )。 33株分离出的流感嗜血杆菌中 ,全部菌株对氯霉素 ,氧氟沙星敏感 ,头孢拉定株 2 1(6 3.6 % ) 、头孢唑林 19株 (5 7.6 % )、去甲万古霉素 2 3株 (6 9.7% ) 、苯唑青霉素 31株 (93.4 % ) 、复方磺鞍甲基异唑 11株 (33.3% )、红霉素 4株 (13.2 % )。结论 :儿童急性呼吸道感染中流感嗜血杆菌有较高的检出率 ,以生物Ⅵ型和Ⅳ型居多。流感嗜血杆菌存在着严重的耐药倾向。Objective:To study Haemophilus influenzae causing Acute respiratory infection in children and the level of its sensitivity to commonly used antibiotics.Methods: By using modified Kirby-Bauer disk agar diffusion method clture(the sample of Haemophilus influenzae of) 78 cases with acute respiratory infection. Results:All HI stains were sensitive to both loxacin and cephosporins. And there were 31(93.4%)strains resistant to oxacillin,23(69.7%) strains resistant to vancomycin,19(57.6%) strains resistant to vancomycin,21(63.6%) strains resistant to cefradine11(33.3%) strains resistant to SMZ-TMP,4(13.2%) strains resistant to erythromycin. Biotype Ⅵ and biotype Ⅳ were the two most common ones. Conclusion: HI is the major cause of Acute respiratory infection in children, Haemophilus influenzae biotype Ⅵ and biotype Ⅳ are the representative strains from ARI children. Haemophilus influenzae was resistant to most antibiotics. [

关 键 词：儿童 急性呼吸道感染 检测 生物分型 抗生素 流感嗜血杆菌 流行性感冒 

分 类 号：R725.117[医药卫生—儿科]