尿石通颗粒质量标准的研究  

Studies on Qulity Control of Niaoshitong Granule

作　　者：祝德秋[1] 罗启剑[1] 崔岚[1] 王平全[1] 

机构地区：[1]上海第二医科大学附属仁济医院,上海200001

出　　处：《中国药师》2003年第5期279-280,共2页China Pharmacist

摘　　要：目的 :建立尿石通颗粒的质量控制方法。方法 :用薄层色谱法对尿石通颗粒中的连钱草进行定性鉴别 ;以芦丁为对照品 ,采用分光光度法法测定颗粒中总黄酮 (以芦丁计 )含量。结果 :薄层色谱中斑点清晰 ,易于识别 ;分光光度法重复性好 ,总黄酮在 8.7～ 6 9.6 μg·ml-1浓度范围内呈线性关系 ,r =0 .9999,平均加样回收率 97.5 % (n =5 ) ,RSD =2 .8%。结论 :本法可有效地控制尿石通颗粒的质量。Objective: To establish a method for qulity control of Niaoshitong granule. Methods: The Glechoma longituba in Niaoshitong was identified by spectrophotometry. The content of total flovoids was determined by spectrophotometry. Result: The spots in the spectrophotometry were clear and to be distinguished well. The liner range of total flovoids (as rutin) was within 8.7 - 69.6 μg·ml -1 ( γ = 0.999 9 ),the average recovery was 97.52% with RSD = 2.76% . Conclusion: The method can be used for qulity control of Niaoshitong granule.

关 键 词：尿石通颗粒 芦丁 分光光度法 

分 类 号：R927.1[医药卫生—药学]