新药坎地沙坦酯的核磁共振谱分析  

NMR analysis of the new drug candesartan cilexetil

作　　者：秦宜德[1] 方敏[1] 徐从贞[1] 罗欣[1] 徐奎 

机构地区：[1]安徽医科大学基础医学院生化系,合肥230032 [2]安徽华康医药科技开发有限责任公司,合肥230031

出　　处：《安徽医药》2003年第2期128-131,共4页Anhui Medical and Pharmaceutical Journal

摘　　要：目的　用核磁共振方法鉴定新药坎地沙坦酯的结构。方法　应用HMQC、HMBC等二维核磁共振技术进行测定。结果　对新药坎地沙坦酯的1H NMR和13C NMR谱信号进行了全归属。AIM To identify the structure of the new drug candesartan cilexetil. METHODS The NMR techniques of HMQC, HMBC, etc were used for measuring and analyzing candesartan cilexetil. RESULTS The 1H NMR and 13 C NMR spectral signals of candesartan cilexetil were properly assigned. CONCLUSIONS The structure of candesartan cilexetil was identified by the techniques of NMR.

关 键 词：新药 坎地沙坦酯 核磁共振谱 分析 结构 

分 类 号：R917[医药卫生—药物分析学]